Postdoctoral Research Associate in Bone and Joint Biomechanics

University of Sheffield - Department of Oncology and Metabolism, Faculty of Medicine, Dentistry and Health

The Department of Oncology & Metabolism at The University of Sheffield provides a dynamic, exciting research environment with an internationally renowned portfolio of basic, clinical and translational research, encompassing the life course.

You will work in a stimulating research environment within Dr Dall’Ara’s research team and part of the Mellanby Centre for Bone Research (http://mellanbycentre.org), which hosts the Skelet.Al facility (http://skeletal.group.shef.ac.uk/), the MRC/ARUK Centre for Integrated Musculoskeletal research in Ageing (CIMA, http://www.cimauk.org/) and The Insigneo Institute for in silico Medicine ( http://www.insigneo.org )

You will work on the enhancement of the assessment of bone and joint properties in preclinical studies, by combining experimental, imaging, image processing and computational approaches. In this project the post-holder will create and validate finite element models for the prediction of bone strength at each time point in mice scanned with in vivo microCT that allows for high-resolution scans of the mice tibia.  Moreover, the post-holder will adapt our protocols to study in details bone changes in the mouse knee to evaluate the effect of OA. Finally, they will be involved in the design and creation of an online service that measures automatically the bone properties in different portions of the tibia and that can be used worldwide by other researchers. This work will lead to an improvement of preclinical research for studying musculoskeletal diseases and for testing new interventions.

Applicants should hold a PhD in Engineering, Physics or related disciplines (or be close to submission), and be familiar with experimental, imaging, image processing and computational modelling techniques for assessment of bone properties, as described in detail in the advert.

You will report to Dr Enrico Dall’Ara and be part of a leading research team.  He will also have the opportunity to interact with the teams of Prof Ilaria Bellantuono (Skelet.Al) and Prof Marco Viceconti (Insigneo).

The post is full time for 30 months.

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Northern England