Research Associate

University of Cambridge - Department of Clinical Neurosciences

Applications are invited for a Post-doctoral research associate position in Spinal Cord Repair John van Geest Centre for Brain Repair Centre, Department of Clinical Neurosciences, University of Cambridge

A research associate position is available in James Fawcett/ Keith Martin group to study axon regeneration in the mammalian spinal cord.

Axon regeneration in the CNS fails because of the inhibitory environment and because axons lose the intrinsic ability to regenerate. Recent work from Cambridge has shown that intrinsic regeneration ability is lost with maturity in the CNS because of changes in axon transport and signalling. The project will develop new regeneration treatments based on trafficking and signalling, and these will be tested using in vivo regeneration models.

The associate will join a group of 6 post-docs and 4 PhD students which focuses on regeneration in the spinal cord and optic nerve. The associate will focus on in vitro models and mechanisms of regeneration, or in vivo regeneration and mechanism experiments.

Two recent papers which form the basis of the project are:

EFA6 regulates selective polarised transport and axon regeneration from the axon initial segment (2017) Richard Eva , Hiroaki Koseki , Venkateswarlu Kanamarlapudi , James W. Fawcett. http://biorxiv.org/content/biorxiv/early/2017/06/14/150037.full.pdf

Selective Rab11 transport and the intrinsic regenerative ability of CNS axons (2017) Hiroaki Koseki Matteo Donegá Brian YH Lam Veselina Petrova Susan van Erp Giles SH Yeo Jessica CF Kwok Charles ffrench-Constant RIchard Eva James W Fawcett https://elifesciences.org/articles/26956

Further information from James Fawcett (jf108@cam.ac.uk) and Richard Eva (re263@cam.ac.uk).

Fixed-term: The funds for this post are available until 30 September 2020 in the first instance.

To apply online for this vacancy and to view further information about the role, please visit: http://www.jobs.cam.ac.uk/job/15099. This will take you to the role on the University’s Job Opportunities pages. There you will need to click on the 'Apply online' button and register an account with the University's Web Recruitment System (if you have not already) and log in before completing the online application form.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

The closing date for applications is the 29th October 2017 with interviews yet to be confirmed by the department.

Please quote reference ZE13416 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Share this job
     
  Share by Email   Print this job   More sharing options
We value your feedback on the quality of our adverts. If you have a comment to make about the overall quality of this advert, or its categorisation then please send us your feedback
Advert information

Type / Role:

Location(s):

South East England