Postdoctoral Training fellow in Quantitative Biology

The Francis Crick Institute

Contract: Fixed-term (4 years), Full time


An exciting interdisciplinary opportunity has come up in the newly established Quantitative Cell Biology laboratory headed by Dr Silvia Santos. We are seeking a creative, highly motivated postdoc with a strong quantitative background, who enjoys working in a collaborative research environment, to investigate how cells decode signals and irreversibly commit to different cell fates.

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a brand new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under a single roof in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; to developing emerging talent and exporting it the rest of the UK; to public engagement; and to helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

Project Scope

The Quantitative Cell Biology laboratory focuses on understanding control principles in cell-decision making. Current areas of research include understanding the interplay between cell division and cellular differentiation during early development. In this context, we have been studying spatio-temporal control and remodelling in cell cycle regulation (Santos et al Cell 2012, Araujo et al Mol Cell 2016) and trying to understand commitment to differentiation, using embryonic stem cells as a model system (Santos et al Nature Cell Bio 2007). There is a strong focus on single cell analysis and combining experimental approaches (based on imaging, proteomics and genomics) and mathematical modelling. Informal inquiries can be sent to

For more information see:

If you are interested in applying for this role, please upload your CV, a cover letter stating your research background and interests and your motivation. Please include names and contacts of two referees.

The closing date for applications is Monday 30th October 2017 at 23:30 pm.

Please note: all offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.

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