Postdoctoral Fellow - Experimental Malaria

Wellcome Trust Sanger Institute - Biological Sciences

Fixed-term for 2 years initially.

The Sanger Institute Malaria Programme integrates genomic and experimental genetic approaches to tackle fundamental questions in malaria biology, and to identify new targets for drug and vaccine development. Our collaborative and multi-disciplinary research teams host a diverse and dynamic group of over 60 scientists led by seven core faculty members.

An opportunity is available for an enthusiastic Postdoctoral Fellow to join the Lee team on a multi-lab collaborative project funded by the Bill and Melinda Gates Foundation. The goal is to systematically investigate new antimalarial targets in Plasmodium falciparum. The project will use a variety of genetic approaches, including CRISPR/Cas9 genome engineering, and capitalizes on existing expertise in the Lee lab and across multiple malaria teams at Sanger developing state-of-the-art CRISPR-based approaches for genome manipulation and drug target validation. The ideal candidate will have demonstrated expertise in parasite culture and genetic manipulation, as well as a strong molecular biology background, and will enjoying working in a collaborative research environment.  

Essential Skills

  • A PhD in microbiology, cell biology, genetics, genomics, or an equivalent area.
  • Research experience in malaria biology or a related relevant area.
  • Experience and excellent practical skills in eukaryotic cell culture techniques.
  • Experience in molecular biology.
  • Experience working in a team.
  • Excellent organization and record keeping skills.
  • Ability to work independently.
  • Basic computer skills.
  • Good communication skills.

Ideal Skills

  • Experience in CRISPR/Cas9 methods.
  • Experience and understanding of biological safety regulations and procedures, particularly in handling human pathogens.

Other information

The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.

The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited’s 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society.

To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.

Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

Please include a covering letter and CV with your application.  

Closing date for applications: 2nd November 2017 , however applications will be considered and reviewed on an on-going basis and therefore the post may be filled before the deadline.