Research Technician

Imperial College London - Department of Life Sciences

South Kensington Campus

The Department of Life Sciences was the top ranked university department in the UK for research intensity in Biological Sciences in REF2014 (Times Higher Education), scoring 100% on our environment.

We are seeking to appoint a pro-active Research Technician to provide technical support to a world-leading and dynamic research team in the Crisanti Laboratory within the Department of Life Sciences at Imperial College London.

The Crisanti Laboratory has pioneered the genetic manipulation of the human malaria mosquito and it is now focused on projects aimed at creating gene drive systems based on the use of DNA endonucleases with the ultimate goal of malaria control by decreasing the reproductive potential of mosquito populations.

The successful candidate will contribute to a joint research effort by the laboratories of Professor Andrea Crisanti at Imperial College London, Professor Keith Joung and Luca Pinello at the Massachusetts General Hospital (Boston, USA), Ahmad Khalil at the Boston University, Chase Beisel at the North Carolina State University and the Polo GGB (Perugia, Italy) towards the development of innovative approaches that will enable temporal and spatial control of gene drive nucleases, tools for countering nuclease-based gene drives as well as novel strategies to surveil for their mutagenic activities and genome-wide off-target detection.

You will interact on a daily basis with researchers of the group and use their molecular biology experience to provide one-on-one assistance in designing and performing DNA cloning and other molecular biology experiments applied to the generation and molecular analysis of modified mosquitos, assist in the assessment of the genotype, phenotype and competitive performance of modified mosquitoes, molecular diagnostic assays, fertility experiments and caged population experiments.

You must have a Bachelor Degree or equivalent vocational qualification in a biological sciences subject. An excellent knowledge of molecular biology theory and extensive experience with DNA cloning and other molecular biology techniques, including RNA extraction, reverse transcription, polymerase chain reaction, gel electrophoresis, DNA purification, blotting and probing is essential.  Previous experience of working with insects or nuclease technologies would be an advantage.

Excellent verbal and written communication skills, accurate record keeping skills, the ability to prioritise tasks to meet deadlines tight deadlines with little supervision are essential.  You must be a highly motivated, innovative and be creative individual with demonstrable ability to learn. You will be expected to work in a collaborative manner, be open-minded with the ability to develop and apply new concepts, and a positive approach to problem solving.

This is a full-time, fixed-term position available for up to 18 months, with the possibility of extension subject to the availability of funding.

For informal enquiries please contact Professor Andrea Crisanti (via l.collyns@imperial.ac.uk) or Dr Roberto Galizi (r.galizi11@imperial.ac.uk)

Our preferred method of application is online via our website http://www3.imperial.ac.uk/employment (please select "Job Search" then enter the job title or vacancy reference number NS 2017 179 PB including spaces into "Keywords").  Please complete and upload an application form as directed. 

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