Senior Laboratory Research Scientist - Protein Expression, Purification and Characterization

The Francis Crick Institute

Contract: Fixed-term (4 years), Full time

Short Introduction/Summary

The Francis Crick Institute seeks to recruit a protein scientist to support institute-wide projects relating to generation and application of recombinant proteins.

The successful candidate will be part of the Structural Biology Science Technology Platform (, which is one of 14 STPs at the Francis Crick Institute. The STPs support research groups with expertise and services in areas that are complementary to the research group’s core activities. The SB STP, comprising 17 members at full complement, interacts with a number of Crick research groups in the fields of protein expression and purification, protein biophysics and structural biology (X-ray crystallography and Cryo-EM).

Project Scope/ Description

The Expression and Purification node of the SB STP supports and collaborates with end-users in a variety of aspects of protein-based research in a lab equipped with state-of-the-art equipment. We are looking for an enthusiastic and self-driven protein scientist to work on short (e.g. delivery of characterized baculovirus) and long-term (e.g. establish the expression and purification of “difficult” proteins using different expression systems) projects in a dynamic environment with scope for learning and implementation of new methods and techniques, and for technology development, depending on the demands from users.

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a brand new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under a single roof in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; to developing emerging talent and exporting it the rest of the UK; to public engagement; and to helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

The closing date for applications is 07 November 2017 at 23:30 pm.

Please note: all offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.

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