Postdoctoral Scientist in Developmental Genetics

University of Oxford - Radcliffe Department of Medicine

We are seeking a motivated and enthusiastic Postdoctoral Scientist to join the research group of Professor Tatjana Sauka-Spengler. The position is fixed-term until 31 May 2018, funded by the Radcliffe Department of Medicine. Sauka-Spengler laboratory is located in the excellent environment of the Weatherall Institute of Molecular Medicine, which has outstanding state-of-the art core facilities including flow cytometry, genomic cores, bioinformatics and The Wolfson Imaging laboratory.

The overall focus of the position is to develop transgenic and molecular tools to visualise and study gene regulatory circuits in the living zebrafish embryos, with a particular emphasis on non-coding RNAs. Development of novel approaches enabling super-resolution of transcriptional activity in the nucleus in the living embryo is central to this project. The post therefore requires high level of competence in laboratory, including extensive experience in molecular biology, zebrafish transgenesis, genome engineering and confocal imaging, as well as aptitude for quantitative and computational approaches in order to develop analysis pipelines.

You will have a PhD in a biomedical related area, extensive experience in zebrafish embryology and transgenesis, molecular biology methods, generation of sequencing libraries for genome-wide analysis of transcriptomes and epigenomes from small cell numbers, epigenomic analyses, super-resolution and/or confocal microscopy. Experience in targeted chromosome conformation capture and computational analysis of genomic datasets are also highly desirable.

Applications for this vacancy are to be made online. You will be required to upload a CV and a supporting statement as part of your online application.

The closing date for this position is 12.00 noon on Friday 20 October 2017.

Please note that the University of Oxford's retirement policy has changed. With effect from 1 October 2017, all employees at Grade 8 and above have a retirement age of the 30 September before the 69th birthday. All employees at Grades 1-7 do not have a set retirement age. Further details are available here: https://www.ox.ac.uk/about/jobs/preemploymentscreening.

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=131353

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