PhD Studentship: Uncovering Novel Therapeutic Targets In Alzheimer’s Disease: Investigating Tau Biology In Alzheimer’s Disease Using The Fruitfly, Drosophila

University of Sussex - Department of Neuroscience

A Ph.D. studentship (42 months) is available from September 2018 under the supervision of Dr Oyinkan Adesakin, Department of Neuroscience, School of Life Sciences.

Deadline: 28th February 2017

Although we have gained an apparent understanding of the molecular processes/proteins underlying Alzheimer’s disease (AD), there still remains no cure or treatment. Alzheimer’s disease (AD) is characterised by the presence of amyloid plaques and tau tangles. Tau pathology appears to be a better predictor of cognitive dysfunction than amyloid deposition in AD. Tau undergoes numerous post-translational modifications, which appear to also play a role in its pathology. In this project, we will use the powerful genetics that the Drosophila model organism affords, to answer really pertinent questions, on the importance/relevance of aspects of Tau biology in AD. This project will utilize expertise in Drosophila genetics & techniques, and will span neuroscience and molecular biology providing a broad and multidisciplinary training for the student.

Please contact Oyinkan Adesakin ( with any project specific queries.

Please submit a formal application using our online application system at, including a CV, degree transcripts and certificates, statement of interest and names of two academic referees. On the application system use Programme of Study- PhD Neuroscience.

Please make sure you include the project title and supervisor’s name with your statement of interest on the application form.

On the application system use Programme of Study – PhD NEUROSCIENCE.

Please make sure you include the project title and supervisor’s name with your statement of interest on the application form.

Please contact Anna Izykowska ( for any application enquiries.

This School funded position, which covers fees and a stipend at standard RCUK rates, is open to Home/EU applicants. Eligible candidates will have recently received an MSc and/or a First or high 2:1 BSc in a relevant subject. Candidates for whom English is not their first language will require an IELTS score of 6.5 overall, with not less than 6.0 in any section.

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South East England