University of Cambridge - Department of Medical Genetics

As part of a CRUK Advanced Clinician Scientist award, a new bioinformatics/software development opportunity, working with Dr Serena Nik-Zainal has arisen. The post holder will have primary responsibility of running the bioinformatics systems within this dynamic and versatile team. The team first developed within the Wellcome Trust Sanger Institute and subsequently moved to the Department of Medical Genetics in the Clinical School at the University of Cambridge in order to further the biological and mechanistic understanding underpinning mutational signatures as well as to take their academic work towards clinical applications.

The successful candidate will be embedded in a multidisciplinary team, will lead on bioinformatics support, will interact with wet-lab as well as dry-lab scientists, pipelining new approaches, software and wrap-around infrastructure to support the team. In addition, the candidate will interact with current web developers in relation to the development of a public-facing website and database that will serve as a resource for mutational signatures. A dynamic individual who can bring new ideas/tools to this up-and-coming area and who is in search of novel technologies to improve bioinformatics systems will be highly valued. 

The successful candidate will have: 

  • A Degree in Bioinformatics or Computer Science (or equivalent)
  • Strong statistical and quantitative skills
  • Excellent programming skills
  • Experience of processing and analysing Next Generation sequencing data
  • Experience working, developing and compiling software tools in a UNIX/LINUX environment
  • Familiarity with statistical modelling and software and experience with large data sets.  

He/ she will enjoy working as part of a team but be experienced with managing own workload and will be able to communicate ideas and results effectively.

Fixed-term: The funds for this post are available until 31 January 2022 in the first instance.

To apply online for this vacancy and to view further information about the role, please visit: This will take you to the role on the University’s Job Opportunities pages. There you will need to click on the 'Apply online' button and register an account with the University's Web Recruitment System (if you have not already) and log in before completing the online application form.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

If you have any questions about this vacancy please contact Michaela Boak, in the first instance.

Please quote reference SS14077 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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South East England