Higher Scientific Officer

Institute of Cancer Research

We are currently seeking a Higher Scientific Officer to provide high-level technical support for a project running in our Histopathology Core Facility, which is based within the Royal Marsden Hospital, but would also require monthly visits to the ICR at Sutton. Applicants should possess a BSc Degree (or equivalent qualification) in biomedical sciences or related field, and must have considerable relevant laboratory experience. The objective of this post is to provide technical support in the optimization and validation of centrosome abnormality measures detected by immunohistochemical methods. Additionally, the post will require provision of histopathology and molecular pathology technical support to research projects in the Breast Cancer Now Research Centre, located at Chelsea ICR site. The work will involve:

  • Tissue preparation, microtomy
  • Immunohistochemical and immunofluorescent staining
  • Validation of immunohistochemical protocols and staining assessment methods
  • Digital imaging and semi-automated image analysis
  • Maintenance of cancer cell culture, preparation of FFPE cell pellets
  • Isolation of biomolecules from formalin-fixed, paraffin-embedded tissues
  • Work-related record keeping
  • Work to strict deadlines
  • Attending and reporting in monthly meetings
  • Technical assessment, quality control and quality assurance of laboratory’s output

Applicants should have considerable experience in histopathology techniques, either from a routine histopathology or research laboratory setting. Thorough knowledge of tissue processing, histological techniques, immunohistochemical techniques and digital pathology systems is essential, alongside with excellent organisational skills. The post holder will have the ability to work independently, as well as to follow guidelines and work within a team environment. The successful candidate will demonstrate high quality laboratory standards, procedures and output.

Appointment will be on a Fixed Term Contract until December 2019, with a starting salary in the range £32,628- £40,619 per annum inclusive based on previous experience.

Informal enquiries are welcome and can be made to Dr Inês Baptista (ines.Baptista@icr.ac.uk)

We consider all applications on merit and have a strong commitment to enhancing the diversity of our staff.

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