Marie Curie Early Stage Researcher (Staff PhD Candidate) in the Field of Quantitative Magnetic Resonance Imaging (ESR9)

University of Sheffield

Applications are invited for a 3 year full-time Marie Curie Early Stage Researcher (staff PhD candidate) in the field of quantitative magnetic resonance imaging. This unique opportunity will enable an exceptional candidate to work in an international research training network, for the European H2020 MSCA ETN project, BQ-MINDED. The successful candidate will be based at the University of Sheffield within the host centre, CISTIB, Centre for Computational Imaging and Simulation Technologies in Biomedicine (, and will register as a staff candidate PhD student. CISTIB performs cutting-edge research in areas of fundamental and applied biomedical imaging & modelling with impact in personalized minimally invasive therapies and active and healthy ageing. Our team has an international and interdisciplinary profile and has a strong commitment to clinical and industrial translation with impact in future healthcare.

The BQ-MINDED project aims to develop breakthroughs in quantitative MR imaging such as MR relaxometry and diffusion MRI. During the research there will be strong emphasis on career development and on achieving impact. B-Q MINDED has the ambition to turn the developed algorithms into diagnostic solutions for improved health and care.

As one of two related posts within this project at the University of Sheffield (ESR9), your specific research, titled “Characterisation of brain tissue structure and vasculature in the micro-scale using dMRI” will involve studying the impact of the microstructural and microvascular changes in dMRI acquisitions, and proposing state-of-the-art signal models for estimating their defining parameters. In a first phase, you will develop computational models dependent on key parameters defining brain tissue. These models will be used for simulating dMRI signals to perform in silico sensitivity analysis of standard dMRI sequences to changes in the microstructure and the microvascular network. In a second phase, you will develop biophysically-oriented models, generalizing previous works, for reducing the variance in the estimation of the aforementioned structural and vascular parameters. The estimation of the model parameters will be assessed by computer simulations as well as using physical phantoms.

This post will involve two short term research stays at the sites of partners within the BQ-MINDED project.

Further details, and a full description of the project can be found at following the links for ESR9. 

Eligibility: Applications are invited from EEA nationals only. Candidates should have a master’s degree in physics, computer science, mathematics, engineering, or related field at the time of appointment, and a background in scientific computing and/or magnetic resonance imaging MRI is desirable. Candidates should have excellent interpersonal communication skills and be a good presenter in written and spoken English.

At the time of recruitment you should be in the first four years (full-time equivalent research experience) of your research career and not have been awarded a doctoral degree. You should also not have resided or carrier out your main activity (work/studies) in the host country for more than 12 months in the 3 years immediately prior to the recruitment date (not including compulsory national service of short holiday stays).

Deadline: 1st Feb 2018, or until there are sufficient suitable applications.

How to apply: Informal inquiries can be made to Prof Alejandro Frangi ( with a copy of your curriculum vitae. To formalise the application, candidates should apply via the BQ-MINDED project website ( selecting ESR9. 

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