PhD Studentship - Simultaneous Measures of Brain and Blood Oxygenation: Revealing the Function behind ‘Functional' Brain Mapping Signals

University of Sheffield

Fully Funded PhD Scholarship in Psychology at the University of Sheffield

This is one of many projects in competition for the current funding opportunities available within the Department of Psychology 

Project title: Simultaneous measures of brain and blood oxygenation: Revealing the function behind ‘functional' brain mapping signals

Primary supervisor: Dr M Jones

Co-supervisor: Dr J Berwick

Project description: A technique called blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) can determine levels of different activity in parts of the living human brain and how malfunctions can occur in disease. However, currently the changes in task related brain tissue oxygenation changes that directly influence blood oxygenation signals are not well characterised and as such, the time course and spatial extent of the fMRI signal is difficult to interpret in terms of the underlying neurometabolic changes and brain activity. The classic technique of polarographic electrode recording of extra cellular tissue oxygen concentration has become in vogue as it is well suited to address this issue. However, no studies have combined this technique with optical imaging spectroscopy measurements of blood oxygenation and as such, the direct relevance of polarographic electrode data to fMRI is uncertain. Thus the present proposal seeks to combine these techniques to further our understanding of the temporal, spatial and functional role of the task evoked changes in cerebral blood oxygenation and as such, directly aid the interpretation of fMRI data.

Start date: 1 October 2018

Requirements: Applicants must have a minimum of a first class or high upper second-class undergraduate honours degree and a distinction or high merit at Masters level in psychology or a related discipline.

Funding: Tuition fees £4,194 per year Living Expenses £14,500.00

Science Graduate School

As a PhD student in one of the science departments at the University of Sheffield, you'll be part of the Science Graduate School. You'll get access to training opportunities designed to support your career development by helping you gain professional skills that are essential in all areas of science. You'll be able to learn how to recognise good research and research behaviour, improve your communication abilities and experience the breadth of technologies that are used in academia, industry and many related careers. Visit www.sheffield.ac.uk/sgs to learn more.

For further details and the application process please visit: www.sheffield.ac.uk/psychology/prospectivepg/phd/funding

Closing date for applications is 5pm Wednesday 24 January 2018

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Type / Role:

PhD

Location(s):

Northern England