Clinical Data Analyst

Institute of Cancer Research

The Institute of Cancer Research, London, is one of the world’s most influential cancer research organisations, with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, and discovered many of the early chemotherapy drugs. Today, The Institute of Cancer Research (ICR) leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment.

The ICR is ranked as the UK’s leading academic research centre. Our unique partnership with The Royal Marsden and ‘bench-to-bedside’ approach allows us to create and deliver results in a way that other institutions cannot. Together we are rated in the top four cancer centres globally.

The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer.

The Institute of Cancer Research is looking for a Clinical Data Analyst to join the Drug Development Unit (DDU) at its Sutton site in Surrey.

The Drug Development Unit, led by Professor Johann de Bono aims to seamlessly integrate preclinical drug discovery, proof-of-principle phase I trials and tumour-specific evaluation of novel agents. It is a conduit for the two-way communication between laboratory and clinical teams that is so essential for successful modern drug development. The unit conducts first-in-man phase I trials involving a range of targets, including growth factor or intracellular signalling, angiogenesis, apoptosis, epigenetics and DNA repair. All trials are underpinned by extensive analysis of biomarkers, both predictive and pharmacodynamics. The DDU includes The Oak Foundation Drug Development Centre (Oak Ward) housed within The Royal Marsden at the Sutton site and specifically designed for phase I clinical trials. Opened in February 2005, the centre provides 10 inpatient beds, five treatment chairs and two outpatient suites, and allows researchers to enter almost 300 patients onto phase I trials each year. This makes the unit one of the largest of its kind in the world. 

The DDU also has an expanding portfolio of investigator-initiated trials of novel targeted agents and combinations of these, including those made available via Cancer Research-UK’s (CRUK) Experimental Cancer Medicine Centres (ECMC) Combinations Alliance. These studies are centrally managed by a dedicated team within the DDU that performs those functions associated with sponsoring early phase trials including project management, monitoring, pharmacovigilance, database development and central data review. The successful applicant will be will be responsible for data management including data review, data analysis and assisting with database set up, implementation and support. They may also be required to perform monitoring visits to participating sites to verify trial activities are compliant with the trial protocol, Good Clinical Practice (GCP), UK Clinical Trials Legislation and Standard Operating Procedures (SOPs).

You should be a graduate in a life science or health related subject and have an understanding of Good Clinical Practice and the drug development process, particularly Phase I clinical trials. Excellent interpersonal skills are required, as is the ability to work to high standards across a variety of tasks with constant regard to scientific and regulatory requirements. Prior experience is not essential, however, experience of working in a clinical trial setting is desirable.

We consider all applications on merit and have a strong commitment to enhancing the diversity of our staff.
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