Research Associate in Computational Biomechanics

University of Sheffield - Department of Mechanical Engineering

Contract Type: Fixed-term until 31 May 2019 with a start date as soon as possible

Faculty: Faculty of Engineering

Summary:

In this exciting post, you will contribute to the development of methods for the generation of individualised multiscale biomechanical models of the musculoskeletal system from imaging and motion analysis data, using data from both in vivo and ex vivo experiments. Such models are used to investigate the biomechanical and mechanobiology determinants of various diseases (for example, osteoporotic fracture, osteoarthritis, juvenile idiopathic arthritis, etc.).

The Insigneo Institute for in silico Medicine is an initiative between the Faculty of Engineering and the Faculty of Medicine at the University of Sheffield and the Sheffield Teaching Hospitals Foundation Trust. Insigneo intends to realise the scientific ambition behind the Virtual Physiological Human, producing a transformational impact on healthcare. While recently established, Insigneo is already considered one of worldwide-leading institutions in the area of in silico medicine research. For more information on Insigneo please see our web pages: www.insigneo.org.

Mechanical Engineering has been a major discipline in the University since its foundation in 1905. In the most recent Research Assessment Exercise (2014), the Department was ranked top 5 in the UK for research excellence. For more information on the Department please see our web site www.sheffield.ac.uk/mecheng

This is an excellent research opportunity to become part of the integrated musculoskeletal biomechanics (IMSB) group of the Insigneo Institute for in silico Medicine (www.insigneo.org) and to contribute to the Multisim Research project (multisim-insigneo.org), one of the largest musculoskeletal biomechanics modelling projects in UK. The research forms part of a programme to create a new modelling framework for the human musculoskeletal system. The post-holder will work on the development of a bone remodeling algorithm where the objective will be to test various mechanical stimuli as potential stimulus that drives bone remodeling. The algorithm will be validated extensively using in vivo longitudinal mice data performed by another Research Associate where the effect of loading on bone remodeling is being measured. The post-holder will be in charge of writing the code, implementing it on an animal-specific mouse tibia, and analyse the results of the different stimuli studied. The post-holder will be required to exchange results with the experimental Research Associate in order to provide a complete validation of the bone remodeling algorithm.

Applicants should hold a PhD in Mechanical Engineering, Computer Science, Bioengineering, Physics or a related discipline and be proficient with finite element analysis. The post-holder will report to Professor Damien Lacroix, Department of Mechanical Engineering, The University of Sheffield. This post is fixed-term until 31 May 2019.

We’re one of the best not-for-profit organisations to work for in the UK. The University’s Total Reward Package includes a competitive salary, a generous Pension Scheme and annual leave entitlement, as well as access to a range of learning and development courses to support your personal and professional development.

We build teams of people from different heritages and lifestyles whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience.

Follow @sheffielduni and @ShefUniJobs on Twitter for more information about what makes the University of Sheffield a remarkable place to work.

Fixed term with a start date as soon as possible and until 31 May 2019

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Northern England