Research Assistant/Associate (Synthetic Biology/Biophysics)

Newcastle University - Faculty of Science, Agriculture & Engineering

Unit: Computing

Salary:

£27,285 to £28,936 (PhD not awarded) 
£29,799 to £38,833 (PhD Awarded)

We are seeking a highly motivated experimental synthetic biology researcher to join Dr Angel Goñi-Moreno’s team at the Interdisciplinary Computing and Complex BioSystems (ICOS) group and the Centre for Synthetic Biology and the Bioeconomy of Newcastle University. You will work on the project “SynBio3D: Establishing the engineering fundamentals of three-dimensional synthetic biology”.

This project seeks to integrate spatial constraints such as distances and molecular crowding into the design and construction of gene regulatory circuits. Each gene sequence and each protein may need a specific physical address in the spatial frame of a cell for optimal performance (see pubs.acs.org/doi/abs/10.1021/acssynbio.6b00397), a fundamental question to be addressed by the project. This will bring spatial resolution to synthetic biology. Single molecules and DNA components will be tracked inside living cells. This project offers a fantastic playground for a researcher in synthetic biology to conduct highly novel research.

You will have a PhD awarded, or be close to obtaining one, with a significant molecular biology, genetic engineering or related component. You will have skills in the construction and validation of synthetic genetic circuits in bacterial cells. You will have knowledge in genome editing techniques. You will have experience in using fluorescence microscopy and, ideally, the visualization of gene expression constituents in individual cells. Experience in super-resolution microscopy is not essential, but will be positively considered. You will possess strong interests in the application of single-molecule tracking to synthetic biology problems.

You will need to be able to work independently as well as part of a team. Good communication skills are essential – our team includes computer scientists, engineers, biochemists, physicists and molecular biologists. Working under the supervision of senior colleagues, you will develop and initiate new collaborations both internally and externally. You will need to write up research results as well as to present our developments in national and international conferences and meetings. You will contribute to identify potential areas of research within the project and develop leadership skills.

The post is available fixed term for 24 months with start date as soon as possible.
Interviews will take place in January 2018, exact date to be confirmed upon invitation.

Click here for further details

Informal email enquiries to Dr Angel Goñi-Moreno are strongly encouraged (angel.goni-moreno@newcastle.ac.uk)

Interdisciplinary Computing and Complex BioSystems (ICOS) group (ico2s.org)
Centre for Synthetic Biology and the Bioeconomy (CSBB, www.ncl.ac.uk/csbb)
SynBio3D: Establishing the engineering fundamentals of three-dimensional synthetic biology” see gow.epsrc.ac.uk/NGBOViewGrant.aspx?GrantRef=EP/R019002/1 and www.ncl.ac.uk/computing/news/item/epsrcfirstgrantsuccessangelgoimoreno.html

Please be advised that due to a new minimum salary threshold of £30,000 per annum imposed by the UKVI, this post may not qualify for University sponsorship under Tier 2 of the points based system. 

The University holds a silver Athena SWAN award in recognition of our good employment practices for the advancement of gender equality, and the University holds the HR Excellence in Research award for our work to support the career development of our researchers. We are also a member of the Euraxess network.

Share this job
     
  Share by Email   Print this job   More sharing options
We value your feedback on the quality of our adverts. If you have a comment to make about the overall quality of this advert, or its categorisation then please send us your feedback
Advert information

Type / Role:

Location(s):

Northern England