Research Associate

Cardiff University - Division of Infection and Immunity, School of Medicine

The role of Hyal2 in mediating hyaluronan synthase 2 antisense-dependent anti-fibrotic cell responses

This post is a postdoctoral research position, funded by Kidney Research UK, to work with Dr Soma Meran and Dr Robert Steadman in the Matrix Biology group of the Wales Kidney Research Unit (WKRU). This group has been investigating the factors that control the pro-fibrotic phenotypic change of cells in progressive fibrotic disease, with relevance to chronic kidney disease. The successful candidate will investigate a novel pathway of cell regulation first described by our group and the project will involve dissecting the role of a newly-described regulator of transcription and its role in controlling the disease-promoting phenotype of cells.

The successful candidate should have excellent personal skills, and a PhD or equivalent qualification in cellular or molecular biology. Experience in a range of cell and molecular biological techniques including cell culture, flow cytometry, qRT-PCR, knockdown and overexpression systems together with light and fluorescence microscopy is essential. A willingness to also develop skills in other laboratory techniques and to help supervise a team of graduate students and research staff would be beneficial. The successful candidate will be joining the Cardiff Centre of the WKRU (http://kidneyresearchunit.wales/en/index.htm), currently consisting of 7 PI’s, 7 postdoctoral fellows, 6 PhD students and 2 technicians.

For further details about the group and the project, please contact Robert Steadman (steadmanr@cardiff.ac.uk).

This post is full time (35 hours per week), available from 1 December 2017 and is fixed term until 30 November 2020.

Please be aware that Cardiff University reserves the right to close this vacancy early should sufficient applications be received.

Cardiff University is committed to supporting and promoting equality and diversity and to creating an inclusive working environment. We believe this can be achieved through attracting, developing, and retaining a diverse range of staff from many different backgrounds who have the ambition to create a University which seeks to fulfil our social, cultural and economic obligation to Cardiff, Wales, and the world. In supporting our employees to achieve a balance between their work and their personal lives, we will also consider proposals for flexible working or job share arrangements.

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Wales