Research Associate in Immunology / Cell Biology

University College London - UCL Division of Infection and Immunity - Institute of Immunity and Transplantation

A postdoctoral research position is available within UCL’s Institute of Immunity and Transplantation at the Royal Free Campus to work on the biology of the CTLA-4 immune checkpoint in the laboratory of Professor David Sansom.

CTLA-4 is a critical regulator of the T cell immune response and patients with deficiencies in CTLA-4 suffer from significant immune dysregulation (Schubert, 2014. Nature Medicine 20:1410). We have identified a novel molecular mechanism of CTLA-4 function (Qureshi, 2011. Science 332:603) and are seeking an individual to further our understanding of the molecular processes that influence CTLA-4 function and regulate T cell immune responses.

Work within the Institute aims to translate advances in basic immunology into improved diagnosis and therapy.The Institute has close links to the Royal Free Hospital and provides an excellent environment for understanding the molecular basis of disease.

The position is funded by the Wellcome Trust and it is available for 3 years in the first instance.

Applicants should have a PhD (or equivalent degree) in immunology or cell biology and a proven track record of publishing in high impact peer-reviewed journals. Experience in molecular biology is essential and experience in protein trafficking, cell biology, confocal microscopy and bioinformatics highly desirable.

Appointment at grade 7 is dependent upon having been awarded a PhD; if this is not the case initial appointment will be at research assistant Grade 6B (salary £30,316 - £31,967 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.

UCL vacancy reference: 1702800

The appointment will be on UCL Grade 7. The salary range will be £34,635 - £41,864 per annum, inclusive of London Allowance.

Applicants should apply online. To access further details about the position and how to apply please click on the ‘Apply’ button below.

If you have any queries regarding the vacancy or the application process, please contact Isabel Lubeiro at

Interview Date: TBC

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