Research Fellow

The University of Edinburgh - The Roslin Institute

Fixed term for 2 years

The post is an exciting opportunity to advance the cutting-edge research of the Roslin Institute, University of Edinburgh. Our group studies the role of RUNX1, FLT3, CSF1R in the development of avian haematopoietic cells, with a special emphasis on the development and function of M-cells, macrophages, monocytes and dendritic cells. The production of healthy chickens requires knowledge of the development and function of the immune system in both embryonic and post-hatch stage chickens. While we can inform our approach to understanding of immune function in chickens through study of the relevant mammalian systems; however, significant differences exist between the birds and mammals. Therefore, a greater understanding of the cells and structures of the avian immune system is required to inform improvements in vaccination technologies and informed breeding strategies. Based in state-of-the-art laboratories, you will join a group using cutting edge genetic engineering/genome editing approaches and embryonic manipulation techniques to develop models to understand the development of the avian immune system. This project will use these models to define the extent and types of lymphoid tissues that are found in the chicken, the critical cells and molecules that underpin the formation of these tissues and the time-frame in which these tissues appear developmentally.

You will possess a PhD (or near completion) in a relevant biological science or laboratory skills relevant to the project objectives, and a record of innovative and high-quality research. Experience of work with avian cell culture, molecular biology and CRISPR-Cas9 mediated genome editing is desirable. Knowledge of (avian) immunology would be advantageous. You will have a proven ability to design, execute and interpret experiments, possess excellent skills in oral and written communication of results, and be highly motivated and work effectively independently or as part of a team.

For more information and to submit an application, please use the ‘apply’ button below.

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