Postdoctoral Scientist - Cell Biology

MRC Laboratory of Molecular Biology

Applications are invited for a post-doctoral position in the laboratory of Dr John O’Neill at the MRC Laboratory of Molecular Biology (LMB), Cambridge to work within a programme aimed at understanding the mammalian cellular circadian clock. Specifically to undertake research to investigate the fundamental molecular mechanisms underlying circadian period determination.

You should have a PhD in a relevant subject or be due to complete their PhD within six months. Particularly useful would be prior experience with circadian research approaches and protein biochemistry. Skills in standard molecular and cell biology techniques, e.g., DNA cloning, western blotting, confocal microscopy, immunoprecipitation, mammalian tissue culture, protein purification and biochemical assays are essential. Practical experience with design/analysis of circadian rhythm experiments, proteomics, rodent models, programming languages (e.g. R, MatLab, Python), bioluminescent and fluorescent reporters, genome editing is desirable.

The successful candidates will be awarded an MRC Career Development Fellowship/MRC Postdoctoral Training Scheme, for a fixed-term period. This is a training and development position for a Postdoctoral Scientist who has recently completed doctoral studies or is moving into a new research discipline.

The MRC Laboratory of Molecular Biology is one of the birthplaces of molecular biology and excels at deciphering the molecular mechanisms of life. It provides an unsurpassed environment for both new and established researchers. Scientists are drawn to the LMB from all over the world, creating a lively and international community for the exchange of ideas and technical innovation.

Working for the MRC provides a whole host of benefits including a final salary pension scheme, Benenden Healthcare membership and excellent holiday entitlement. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.

For further information of the research undertaken at the LMB, please visit:

For informal enquiries please contact Dr John O’Neill ( or visit the group's website:

To apply and access full details of the vacancy please visit our job board at If you are unable to apply online please contact us at

Final appointments will be subject to a pre-employment screening.

The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme

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