Postdoctoral Computational Chemistry Engineer

University of Oxford - Nuffield Department of Medicine (NDM), Structural Genomics Consortium

Applications are invited for a Postdoctoral Computational Chemistry Engineer to work under the supervision of Professor Frank von Delft on a research project for a period of 12 months (until 31 December 2018) in the first instance with the possibility to extend for a further year. The project involves finding small molecule drugs and tool compounds using the world first fragment screening facility (XChem) developed between the SGC Oxford and Diamond Light Source. Find out more about the XChem project at

You will hold a PhD in computational or medicinal chemistry or have submitted a PhD thesis prior to taking up the appointment. You should have extensive expertise in computational or synthetic chemistry in a drug discovery context. Most importantly you will have an interest in developing methods and tools to improve the efficiency of drug discovery.

You will be responsible for generating computational and experimental tools to streamline the design and synthesis of follow-up compounds for fragment-based drug design. You will work as part of the XChem team building infrastructure and novel tools that will hopefully provide a step-change in efficiency of this early stage in drug-discovery.

You will be expected to manage your own academic research and administrative activities, to supervise and educate junior co-workers and take part in this highly collaborative team project.

In your role as Postdoctoral Computational Chemistry Engineer, you will be well-organised, with the ability to work as part of a team and to collaborate with colleagues on a range of diverse projects.

The post will be based between the Research Complex at Harwell and Structural Genomics Consortium, Oxford.

You will be required to upload a CV and supporting statement which explains how you meet the selection criteria for the post.

Only applications received before 12.00 noon on 22 January 2018 will be considered.

Please note that the University of Oxford's retirement policy has changed. With effect from 1 October 2017, all employees at Grade 8 and above have a retirement age of the 30 September before the 69th birthday. All employees at Grades 1-7 do not have a set retirement age. Further details are available here:

Closing Date: 22-JAN-2018 12:00

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