Postdoctoral Research Associate in Molecular Mechanisms of Enterobacterial Resistance to Complement

University of Oxford - Department of Biochemistry

South Parks Road, Oxford

We are seeking to appoint a postdoctoral research associate with experience of bacterial live cell imaging to work in the laboratory of Professor Colin Kleanthous. The post is part of a joint award with Professor Peter Taylor at University College London to investigate molecular mechanisms of enterobacterial resistance to complement. The post in London will exploit a range of in vitro and in vivo approaches to understand complement resistance in Escherichia coli and Klebsiella pneumoniae while the post in Oxford will develop fluorescence imaging approaches to investigate how such resistance affects the distribution of complement components relative to supramolecular assemblies of outer membrane proteins.

Applicants should possess, or expect to obtain soon a PhD in molecular microbiology, biochemistry or molecular biophysics and should have experience in working with bacteria and imaging fluorescently-labelled proteins by microscopy. You should be willing to learn new techniques and apply them in an interdisciplinary research environment, and be able to keep detailed laboratory records and report on progress at regular intervals. Applicants with experience in confocal fluorescence microscopy, total internal reflection fluorescence microscopy and/or 3D-structured illumination microscopy are particularly encouraged to apply.

This full-time fixed-term post is funded by the Medical Research Council for up to 3 years in the first instance and is based at the Department of Biochemistry, South Parks Road, Oxford.

This position is graded on the University’s Grade 7 scale, the actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

Further particulars, including details of how to apply, can be obtained from the document below.

The closing date for applications is 12.00 noon on 5 February 2018 with interviews for shortlisted candidates to be held as soon as possible thereafter.

Please note that the University of Oxford's retirement policy has changed. With effect from 1 October 2017, all employees at Grade 8 and above have a retirement age of the 30 September before the 69th birthday. All employees at Grades 1-7 do not have a set retirement age. Further details are available here:

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