Research Assistant/Associate in Preclinical MRI Physics

University of Glasgow - Research Institute of Neuroscience & Psychology

College of Medical, Veterinary and Life Sciences

Salary £28,098 - £31,604/£34,520 - £38,833 per annum

The post holder will contribute to the following project 'The identification of myocardial infarction (MI) patients who can benefit from revascularisation remains one of the most challenging aspects of cardiology [1]. Ideally, an assessment of viability following myocardial ischaemia requires knowledge of both myocardial blood flow (MBF) and aerobic metabolism (myocardial oxygen consumption MVO2). Unfortunately, the current gold standard for imaging aerobic metabolism, 15O2 positron emission tomography (PET), is not practical for routine clinical use [2]. This project takes the first steps in developing a safe alternative approach based on Magnetic Resonance Imaging (MRI), using intravenous delivery of oxygen carriers pre-saturated with 17O2 gas and 17O decoupled 1H MRI. The method will be validated in vivo using a pre-clinical model of myocardial infarction. An MRI based method for imaging aerobic metabolism, combined with MRI assessment of perfusion, would allow better assessment of myocardial viability directly via "flow-metabolism mismatch'.

The post-holder will also be expected to contribute to the formulation and submission of research publications and research proposals as well as help manage and direct this complex and challenging project, as opportunities allow.

This post is full time and has funding for up to 2 years in the first instance.

Informal enquires may be made to Dr William Holmes (william.holmes@glasgow.ac.uk)

Apply online at: https://www.gla.ac.uk/explore/jobs/

It is the University of Glasgow’s mission to foster an inclusive climate, which ensures equality in our working, learning, research and teaching environment.

We strongly endorse the principles of Athena SWAN, including a supportive and flexible working environment, with commitment from all levels of the organisation in promoting gender equity.

The University is committed to equality of opportunity in employment.

The University of Glasgow, charity number SC004401.

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