Research Fellow in Cardiovascular Sciences

University of Leeds - Faculty of Biological Sciences - School of Biomedical Sciences

Are you an ambitious researcher looking for your next challenge? Do you have an established background in cellular cardiovascular research? Do you want to further your career in one of the UKs leading research intensive Universities?

The potassium channel Kv1.5 is a major repolarizing K+ channel within atrial tissue, and represents an attractive pharmacological target in the treatment of atrial fibrillation. The aim of this project is to evaluate the oxidative modulation of Kv1.5 in established models of AF, and establish how this can be regulated by exogenous and endogenous carbon monoxide and hydrogen sulphide. In so doing, we aim to identify a novel means by which AF can be treated via regulation of gasotransmitter formation. We are looking for a highly motivated post-doctoral cardiovascular researcher with relevant experience including cellular cardiac electrophysiology, the use of paced HL-1 cells as a model of atrial fibrillation, expression of recombinant ion channels, measurement of reactive oxygen species and siRNA gene silencing. Experience studying the role of gasotransmitters in cardiac cell function would be an advantage.

The University of Leeds and the Faculty of Biological Sciences are committed to providing equal opportunities for all and offer a range of family friendly policies. The University is a charter member of Athena SWAN (the national body that promotes gender equality in higher education), and the Faculty of Biological Sciences gained a Bronze award in 2014 and submitted an application for a Silver award in April 2017. We are proud to be an inclusive Faculty that values all staff, and are happy to consider job share applications and requests for flexible working arrangements from our employees. Our Athena SWAN webpage provides more information. 

To explore the post further or for any queries you may have, please contact:

Professor Derek Steele, Professor of Cellular Physiology

Tel: +44 (0)113 343 2912, email:

Location: Leeds - Main Campus
Working Time: 100%
Contract Type: Fixed Term (2 years - due to funding)

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Northern England