Postdoctoral Fellow (Computational)

Wellcome Trust Sanger Institute - Biological Sciences

Fixed term for 3 years

The Hemberg group is primarily interested in developing quantitative methods and models for analysing gene expression and gene regulation. We are particularly interested in working with data generated from high-throughput technologies, making sure that the software used to analyse this data is computationally and statistically rigorous. We are looking to appoint a computational post-doctoral fellow who is interested in applying their skills to transcriptomics and genomics. Prior experience of working with next-generation sequencing data is not necessary. We are looking for someone with strong mathematical and/or programming skills who is willing to learn about problems in molecular biology.

  • To carry out development of computational methods for analysis of high throughput genomics data, with a focus on single-cell analysis or regulatory genomics
  • To plan a programme of research that is original but fits within the general research area of the team, taking into account the relevant literature, own experience, and advice from the team leader and other appropriate scientists
  • To carry out the research, developing the practical skills required for successful completion
  • To analyse data and write up results for publication, and to deal with all aspects
  • of the publication process
  • To communicate the results through other relevant means, such as talking or presenting posters at scientific meetings
  • To seek appropriate training, including taking an active part in any training programmes organised for postdoctoral training fellows. This will include transferable skills training
  • To take a full part in the general duties of the team, and to pass on skills and knowledge to other team members and visitors. To take part in wider Sanger Institute activities as appropriate
  • To complete training period in a timely manner, publish the research and document any unpublished data and materials before moving on to a new position

The fellow will help shape the future direction of the research group and have the opportunity to develop their own research projects within the scope of the group’s interests. Supervisor - Dr Martin Hemberg

Essential Skills

  • PhD (or equivalent) in Quantitative Biology, Mathematics, Physics or Computer Science
  • Ability to independently solve complex scientific/technical problems and manage scientific projects
  • Programming skills (e.g. R, C, Python, Julia, Java, Matlab) Mathematical modelling or machine learning
  • Excellent communication skills
  • Self-motivation and diligence
  • Good publication track record

Ideal Skills

  • Ability to train and develop others in scientific techniques, including working with an international interdisciplinary group of scientists
  • Experience with cloud computing

Other information

The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.

The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited’s 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society.

To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.

Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

Please include a covering letter and CV with your application.

The closing date has been extended to: 1st February 2018, however applications will be considered and reviewed on an on-going basis and therefore the post may be filled before the deadline.