Marie Sklodowska-Curie ITN Early Stage Researcher Post in Neurochemical Studies of Tinnitus and Hearing Loss Using Magnetic Resonance (MR) Imaging (full time, fixed term)

University of Nottingham - Clinical Neuroscience

Applications are invited for the Marie Sklodowska-Curie Innovative Training Network (TIN-ACT TINnitus Assessment, Causes and Treatments). The successful applicant will also register for a PhD at the University of Nottingham.

TIN-ACT is an exciting and unique collaboration between leading European universities, industry and partner organizations to provide high-quality training for future interdisciplinary scientists. This position will be part of the TIN-ACT www.tinact.eu cohort of 15 early stage researchers who will be undergo innovative interdisciplinary and intersectoral training programme co-ordinated by University Medical Centre Groningen.

This project is focused on measuring alterations of the brain’s neurochemistry in tinnitus and hearing loss using non-invasive Magnetic Resonance Spectroscopy (MRS) at 3T and 7T. This innovative approach makes use of advanced MRI technology (MEGA-PRESS detection of γ-aminobutyric acid [GABA] and Glutamate [Glu]) to measure local changes in inhibitory and excitatory neurotransmitters in order to understand adaptive and maladaptive brain processes in tinnitus and hearing loss. GABA levels appear to be reduced in tinnitus. This project will investigate GABA and Glu at rest and dynamically during auditory stimulations with concurrent recording of sensory perceptions. 

The work will be carried out at the Sir Peter Mansfield Imaging Centre, in collaboration with the NIHR Nottingham Biomedical Research Centre (MRI and Hearing themes, http://www.hearing.nihr.ac.uk/). The successful applicant will join a large and vibrant research group in Nottingham and will benefit from excellent inter-disciplinary supervisory support that spans imaging, neuroscience, hearing science and statistics. 

The successful candidate will learn about established and advanced MR spectroscopy methods, and research with patients with tinnitus and hearing loss. Two funded secondments are planned in years 1 and 2 (up to 3 months each); (i) the University Medical Centre Groningen, Netherlands, and (ii) Cochlear Research and Development Limited, UK.

Candidates must be in possession of (or expected to obtain) a first class or upper 2.1 honours degree (or equivalent), or an MSc/MA, in Physics, Life Sciences or Computer Science, or other relevant scientific discipline. Experience of conducting human experimental studies, or working with adults who have hearing problems will be of particular advantage, but not essential. Candidates should also have excellent communication and team-working skills, be self-driven and highly motivated. 

Candidates will also be required to meet the Marie Sklodowska-Curie Early Stage Researcher eligibility criteria: http://ec.europa.eu/research/participants/data/ref/h2020/wp/2016_2017/main/h2020-wp1617-msca_en.pdf pp58-60 In particular, at the time of recruitment, candidates must have had less than four years full-time equivalent research experience and must not have already obtained a PhD. Additionally, they must not have resided in the (host country) UK for more than 12 months in the three years immediately before the appointment. 

This full-time post is available to start in September 2018 and is offered on a fixed-term 36-month contract. The post benefits from a highly competitive and attractive salary, plus mobility and family allowances as applicable. 

The University of Nottingham values diversity and are committed to equality of opportunity. The University holds a Silver Athena SWAN Award in recognition of its commitment to advancing women's careers in science. You can read more about what this means at: http://www.athenaswan.org.uk/ 

Informal enquiries may be addressed to Prof Dorothee Auer, tel: +44 (0) 115 82 31178 or email: dorothee.auer@nottingham.ac.uk, or Dr Katrin Krumbholz, email: katrin.krumbholz@nottingham.ac.uk. Formal applications must be made through the University’s online application system

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Type / Role:

PhD

Location(s):

Midlands of England