Research Technician: Systems Genetics and Precision Health

European Molecular Biology Laboratory (EMBL)

The European Molecular Biology Laboratory (EMBL) is one of the highest ranked scientific research organisations in the world. The Headquarters Laboratory is located in Heidelberg (Germany), with additional sites in Grenoble (France), Hamburg (Germany), Hinxton (UK), Rome (Italy) and Barcelona (Spain).

We are looking for a Research Technician specialized in developing and optimizing next generation sequencing technologies to join the ‘Systems Genetics and Precision Health’ group led by Dr. Lars Steinmetz. The group develops and applies genome-wide technologies to elucidate the genetic basis of complex phenotypes, the functions and mechanisms of transcription and the genetic and molecular systems underlying diseases. The successful candidate will contribute to the development of novel single-cell genomic methods and their application to the study of acute myeloid leukemia. He or she will work with both custom and commercially available, cutting-edge single-cell genomic tools, and will be embedded in a strong collaborative network including the German Cancer Research Center (DKFZ) as well as the university clinics.

The Research Technician´s responsibilities will include:

  • Testing, developing and evaluating new tools, reagents and experimental protocols, in particular in the field of next generation sequencing, single-cell RNA sequencing, and CRISPR
  • Generating large-scale datasets using these protocols
  • Working in close collaboration with the EMBL Genomics Core Facility to optimize the aforementioned protocols;
  • Supporting members of the laboratory throughout their scientific projects;
  • Training new group members and visitors in technologies and protocols used in the laboratory.

The Research Technician is expected to contribute to scientific projects at all stages, ranging from experimental design to manuscript preparation.

The appointed applicant will report to the Group Leader and the Lab Manager.

Qualifications and Experience
Applicants should have an appropriate University degree or equivalent certificate from a technical training college in a relevant scientific subject. The successful candidate will be familiar with the fundamentals of cancer biology, stem cell biology and epigenetics. (S)he will have hands-on experience in high throughput technologies and particular expertise in next generation sequencing methodology and techniques. Additional skills in as many as possible of the following fields are desirable: Single-cell RNA sequencing, genetic engineering (both classical cloning protocols and CRISPR), human tissue culture and flow cytometry. The appointed candidate will be capable of working independently, but also enjoy being part of an interdisciplinary team of scientists within a highly collaborative international atmosphere. Flexibility as well as excellent communication skills and fluency in written and verbal English are essential.

Application Instructions
Please apply online through

Additional Information
EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation. Please note that appointments on fixed term contracts can be renewed, depending on circumstances at the time of the review.

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* Salary has been converted at the prevailing rate on the date placed