Fully funded PhD in Integration of Microfluidic Assembly with CMOS Electronics for Point-of-care Devices

The University of Edinburgh - Centre for Doctoral Training for Intelligent Sensing and Measurement: School of Engineering

First supervisor: Dr Srinjoy Mitra (School of Engineering, University of Edinburgh) 

Contact email: Srinjoy.Mitra@ed.ac.uk

Point-of-care (POC) medical diagnostic devices are a rapidly growing field of research both in the western world and in Low-and-Middle-income countries. One common feature of POC devices is that they all require complex microfluidic manipulation of samples such as blood, urine, saliva, and liquid reagents, and so on. Therefore, it is essential for POC IVD systems to have built-in liquid-handling capabilities in order to achieve the efficiencies of traditional laboratory based operations. While CMOS (Complementary Metal Oxide Semiconductor) integrated circuits are the backbone of sensor electronics necessary for such POC applications, the integration of microfluidic assembly with CMOS is still in its nascent state. This is of particular importance when the POC devices are targeted for hand-held applications and operated by patients or health-care providers with low technological knowhow. In a resource poor setting (e.g., remote LMIC locations), it is expected that the sensor electronics and the micro-fluidic assembly will not only be integrated in hand-held format but will also operate with minimal external intervention. This necessitates number of innovations that will ensure sample filtering, reagent reservoirs, active pumps, wash steps etc., all in a tiny match-box sized device.

This PhD a 1+3 PhD, with one year of MSc-level, multi-disciplinary training and three years of PhD Research carried out within the Centre for Doctoral Training for Intelligent Sensing and Measurement, at the School of Engineering in the University of Edinburgh. The School is part of the Edinburgh Research Partnership, where 94% of research was judged to be world-leading or internationally excellent in the last Research Excellence Framework assessment. https://www.eng.ed.ac.uk/about/news/20141218/ref-2014

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Type / Role:

PhD

Location(s):

Scotland