|Salary:||£33,199 to £39,609 per annum (Grade 6)|
|Placed On:||11th October 2018|
|Closes:||11th November 2018|
A new major translational award has been awarded by the Medical Research Council, worth £2.5M. This complements an exciting and mature portfolio of Drug Discovery funding awarded to Prof Simon Ward and Prof John Atack from Cardiff University.
The grant will look at Fragile X syndrome (FXS) - a leading inherited cause of autism and intellectual disabilities which affects approximately 1 in 5000 individuals. There are no currently approved drugs for the treatment of FXS which can cause a wide range of difficulties with learning, as well as social, language, attentional, emotional, and behavioural problems. There is therefore an urgent need for new therapeutic approaches for this disorder.
Proof of concept experiments have shown that inhibition of LIMK1 (a gene which provides instructions for making a protein that is highly active in the brain) could represents an attractive new therapeutic approach to FXS.A world leading team of specialists have been assembled and further scientist will be recruited to Cardiff to address the enormous challenge of bringing forward new medications for FXS. Collaborations will take place across the UK and will include Oxford University, University of Dundee as well as academic colleagues in Germany, San Francisco, Montreal and Chicago. We will also be working closely with The Fragile X Society, a charity who provide practical guidance to support to individuals and families affected by FXS.
This will enable a link to patients and clinicians involved to help us work together effectively to work towards the mission to find an effective treatment for FXS.
To conduct research within Medicinal Chemistry and contribute to the overall research performance of the University, carrying out research leading to the publishing of work in high-quality journals. To pursue excellence in research and to inspire others to do the same.
The posts will be based at Cardiff University and will be part of a multi-disciplinary drug discovery team. For informal inquiries, please contact firstname.lastname@example.org
In Higher Education, female and BME (black and minority ethnic) staff are underrepresented in senior academic roles. Applications are therefore particularly welcome from applicants who identify as female and/ or BME. We also welcome applications from members of the LGBT+ Community.
This post is full-time fixed-term and is available until 31 January 2021. This post will be available from 1 February 2019.
Salary: £33,199 - £39,609 per annum (Grade 6). It is not anticipated that an appointment will be made above grade 6 point 33, currently £36,261 per annum.
Interviews will be held week commencing 19 of November.
Date Posted: Thursday, 11 October 2018
Closing date: Sunday, 11 November 2018
Please be aware that Cardiff University reserves the right to close this vacancy early should sufficient applications be received.
Cardiff University is committed to supporting and promoting equality and diversity and to creating an inclusive working environment. We believe this can be achieved through attracting, developing, and retaining a diverse range of staff from many different backgrounds who have the ambition to create a University which seeks to fulfil our social, cultural and economic obligation to Cardiff, Wales, and the world. In supporting our employees to achieve a balance between their work and their personal lives, we will also consider proposals for flexible working or job share arrangements.
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