|Funding for:||UK Students, EU Students|
|Funding amount:||£14,777 UKRI annual stipend (2018/19 rate) + tuition fees + training support grant|
|Placed On:||22nd October 2018|
|Closes:||7th January 2019|
Lead supervisor: Dr Lauren Cowley, Department of Biology and Biochemistry, University of Bath, email: email@example.com
This project is one of a number that are in competition for funding from the NERC Great Western Four+ Doctoral Training Partnership (GW4+ DTP). For further details about the programme, please see https://nercgw4plus.ac.uk/ .
Full Project Description
Genomewide association studies (GWAS) are a powerful tool in discovering the genetics underlying observed important phenotypes and have been used very successfully in human genetics for several heritable diseases. In bacteria that reproduce asexually, the challenge with GWAS is the high linkage between polymorphisms due to low levels of recombination. A lot of the mutations or genes in bacterial genomes are not acquired independently and it is therefore difficult to differentiate the mutation or gene that is causing the phenotype change from those that are simply hitch hiking with it (linkage disequilibrium).
Methods developed to achieve bacterial GWAS results of high confidence could be extremely useful in determining the genetic elements associated with phenotypes of environmental importance, such as toxin production, environment survivability, antibiotic resistance or host niche. Previous studies by co-supervisors Professor Sam Sheppard and Dr Ruth Massey (Sheppard et al., 2013, Recker et al., 2017) have shown the capabilities of GWAS in bacteria.
The aims of the studentship will be:
NERC GW4+ DTP funding is for 3.5 years and is open to UK and EU applicants who have been resident in the UK for 3 years or more.
A studentship will provide UK/EU tuition fees, a stipend in line with the UKRI rate (£14,777 per annum for 2018-19) and a generous budget for research expenses and training. For further information please visit: https://www.bath.ac.uk/guides/natural-environment-research-council-nerc-gw4-doctoral-training-partnership/
You may apply for more than one project if you wish but you should submit a separate personal statement relevant to each one.
Further information on the Department of Biology & Biochemistry may be found here http://www.bath.ac.uk/departments/department-of-biology-biochemistry/
Anticipated start date: 30 September 2019
Type / Role: