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Scientific Technical Officer - Single Particle Electron Microscopy at the EMBL Hamburg Unit

European Molecular Biology Laboratory (EMBL)

Location: Hamburg - Germany
Salary: Grade 6 or 7, depending on experience and qualification
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 6th December 2018
Closes: 13th January 2019
Job Ref: HH00157

Organisation data: Wilmanns Group

About the team/job

The research portfolio of the EMBL Hamburg Unit mainly focuses on research of large protein complexes and machineries involved in host/pathogen interactions during the infection of bacterial and viral pathogens. Specific research interests are on nutrient transporters (C Löw), host/virus interactions (J Kosinski) and secretion machineries (M Wilmanns). While making use of EMBL-operated state-of-the-art on-site infrastructures at the Petra III synchrotron storage ring for X-ray based structural biology as well as Sample Preparation and Characterization (SPC), the complexity of projects under investigation essentially require an integrative structural biology approach that includes the use of electron microscopy. New opportunities emerge with the establishment of the cryo-electron microscopy facility at the Centre for Structural Systems Biology (CSSB), complemented by the availability of a transmission electron microscope at the nearby XFEL Biology Infrastructure (XBI) laboratory and the state-of-the-art electron microscopy facility at the EMBL headquarters in Heidelberg.

Your role

Your task will be to establish electron microscopy expertise at the EMBL Hamburg Unit and to train and supervise fellows in the relevant steps required for structure determination by single particle cryo-electron microscopy. This includes support from experimental design, sample preparation, sample screening (negative stain and cryo condition), data acquisition, processing and interpretation. In addition, there will be opportunities to lead relevant scientific projects independently and to acquire new skills in advanced electron microscopy techniques. You will be affiliated with the research group of Matthias Wilmanns. Your expertise will be accessible to all interested research groups and teams from the EMBL Hamburg Unit.

You have

You should have a PhD in a relevant field, ideally two years of postdoctoral experience, a proven record of scientific accomplishments, international experience, scientific ambition excellent communication skills, and previously demonstrated expertise in single particle electron microscopy and biophysical approaches including sample preparation.

You might also have

Additional expertise in X-ray crystallography and cell biology including imaging would be advantageous.

Why join us

EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation with a very collegial and family friendly working environment. The remuneration package comprises a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits, as well as financial support for relocation and installation, including your family. Scientists at the EMBL Hamburg Unit benefit from cutting-edge technology to accommodate their research, with on-site synchrotron radiation beamlines operated by EMBL and opportunities for collaboration with colleagues from all six EMBL units.

What else do I need to know

We are Europe’s flagship research laboratory for the life sciences – an intergovernmental organisation performing scientific research in disciplines including molecular biology, physics, chemistry and computer science. We are an international, innovative and interdisciplinary laboratory with more than 1600 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton near Cambridge, Hamburg, Grenoble and Rome.

Our mission is to offer vital services in training scientists, students and visitors at all levels; to develop new instruments and methods in the life sciences and actively engage in technology transfer activities, and to integrate European life science research.

Informal inquiries should be sent to:

Please note that appointments on fixed term contracts can be renewed, depending on circumstances at the time of the review.

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* Salary has been converted at the prevailing rate on the date placed
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