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Postdoctoral Fellow - Single Cell Genomics

European Molecular Biology Laboratory (EMBL)

Location: Heidelberg - Germany
Salary: Stipend
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 7th December 2018
Closes: 13th January 2019
Job Ref: HD01424

About the team/job

EMBL is seeking a postdoctoral scientist to join Dr. Jan Korbel's group in the Genome Biology Unit to work on single cell genomics, with a focus on exploring and integrating genetic and epigenetic variation in human cell types. Scientists qualifying for this position could either have an experimental or a largely computational background. While there has been ample progress in developing methods for sequencing transcriptomes in single cells, much less progress has been made in our understanding of genetic variation in single cells. The Korbel group is developing methodologies that allow joint analyses of genetic and epigenetic variation in scalable single cell sequencing assays. In the context of an ERC Consolidator Grant recently awarded to the group, the group is now launching research projects to unravel patterns of clonal genetic and epigenetic evolution in the human genome, and to understand processes of genome dynamics. 

Your role

The post holder will join an interdisciplinary team and will be responsible for the generation of single cell data and/or computational analyses to obtain new biological insights, as well as follow-up studies within an inspiring lab atmosphere and an environment in which unique technologies are being developed. Experience in single cell data analysis or generation will not be a requirement, but would be considered a plus. Frequent interaction with lab members and collaborators will be a crucial part of the job. 

You have

Applicants should have a PhD in the biological sciences, bioinformatics, computer science, physics or a related field, and proven research experience in a relevant field. The ideal candidate is motivated to work in an international team on interdisciplinary projects and enjoys to work in a highly collaborative atmosphere. Fluency in English is essential.

You might also have

Curiosity and experience in tackling biological questions. 

Why join us

Why not! Well, EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation with a very collegial and family friendly working environment. The remuneration package comprises from a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits, and the availability of an excellent child care facility on campus. 

What else do I need to know

The Korbel group at the European Molecular Biology Laboratory (EMBL) combines experimental and computational approaches, including single-cell sequencing technology, to unravel determinants and consequences of germline and somatic genetic variation. Our group is using bulk as well as single cell-based omics approaches for investigating mechanisms behind complex phenotypes in humans, ranging from common diseases including cancer to ageing. An over-arching theme centers on the formation and selection of germline and somatic genetic variation in health and disease states, in particular genomic structural variation (SV).

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