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PhD Studentship: NMR Methodology Development Across Disciplines of Magnetic Resonance

The University of Edinburgh

Qualification Type: PhD
Location: Edinburgh
Funding for: UK Students, EU Students
Funding amount: £15,009 annual stipend and covers tuition fees
Hours: Full Time
Placed On: 22nd February 2019
Expires: 22nd May 2019
 

Supervisors: Prof Dušan Uhrín
Contact: dusan.uhrin@ed.ac.uk

This 3 year PhD studentship is available to start on 1st of September 2019. The studentship is fully funded for 36 months and covers tuition fees and an annual stipend (starting at £15,009 per annum) for a candidate satisfying EPSRC criteria: https://www.epsrc.ac.uk/skills/students/help/eligibility/

The programme seeks to advance NMR methodology, with an emphasis on liquid-state NMR, however, solids and in vivo applications will also be considered. Part of the program will align with the on-going research in applying and developing further recently introduced SHARPER methodology, but also in other hot topics of the day, such as analysis of complex mixtures, pure-shift methodology and the emerging field of benchtop NMR.

Access will be provided to six 300-800 MHz NMR spectrometers (several equipped with cryoprobes) in the School of Chemistry central NMR facility. The PhD student will be working alongside a recently appointed postdoctoral research associate working on an EPSRC funded 3 year project: “SHARPER NMR: fast and accurate analysis of molecules, reactions and processes” but his/her remit will not be limited to this topic. For more information about the Uhrín group please see http://uhringroup.wixsite.com/nmrgroup and recent publications given below.

The successful candidate will possess, or expect to obtain, a first class or upper-second class undergraduate degree (or equivalent) chemistry or physics, an aptitude and strong interest in developing their skills in area of NMR methodology and computer assisted interpretation of NMR spectra.

In the first instance, informal enquiries (accompanied by a CV) should be directed to Prof. Dušan Uhrín Dusan.Uhrin@ed.ac.uk . The position will remain open until filled.

The School of Chemistry holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. The University is a member of the Race Equality Charter and is a Stonewall Scotland Diversity Champion, actively promoting LGBT equality. The University has a range of initiatives to support a family friendly working environment. See our University Initiatives website for further information. University Initiatives website: https://www.ed.ac.uk/equality-diversity/help-advice/family-friendly.

Recent publications

  1. Jones, A.B., Lloyd-Jones, G.C., Uhrín, D, SHARPER reaction monitoring: generation of a narrow line-width NMR singlet, without X-pulses, in an inhomogeneous magnetic field, Anal. Chem. 89 10013–10021 (2017).
  2. Kew, W., Bell, N.G.A., Goodall, I., Uhrín, D., Advanced solvent signal suppression for the acquisition of 1D and 2D NMR spectra of Scotch Whisky. Magn. Reson. Chem. 55, 785–796 (2017).
  3. Brodaczewska, N., Košťálová, Z., Uhrín, D., (3, 2)D 1H, 13C BIRDr,X-HSQC-TOCSY for NMR structure elucidation of mixtures. Application to complex carbohydrates, J Biomol. NMR 70,115–122 (2018).
   
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