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Research Fellow/Associate in Computational NMR Structural Biology

University of Leicester - Leicester Institute of Structural and Chemical Biology/Molecular and Cell Biology

Location: Leicester
Salary: £34,189 to £39,609 Grade 7, per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 9th April 2019
Closes: 8th June 2019
Job Ref: 877

The University of Leicester has initiated the Leicester Institute for Structural and Chemical Biology (LISCB) as a centre of research excellence.  Aided by >£4m in investments in both equipment and new appointments, the research within LISCB targets the functioning of biological relevant molecules through integrated approaches. Biomolecular Nuclear Magnetic Resonance (NMR) is a major experimental technique within LISCB, used for studying structure, interactions and dynamics.

LISCB hosts the Collaborative Computational Project for NMR (CCPN; ), chaired by Prof Vuister. Over the past sixteen years, CCPN has provided the tools and knowledge to maximise the impact of biological NMR studies. The CCPN software facilitates data analysis and software integration, and is used in ~300 laboratories across the world. The project actively promotes the exchange of knowledge, provides training and best practices for the NMR community.  The 28 UK and international partners of CCPN jointly cover all aspects of biomolecular NMR and together we develop new state-of-the-art tools in NMR data analysis and NMR structural biology.  

The CCPN project is seeking to recruit a talented and highly motivated research scientist/software developer to design and implement new technologies in biological NMR. We are seeking an individual with relevant expertise in biological NMR OR a software developer with experience highly relevant to the project. This is an exciting opportunity to contribute to an important international project that serves a central role in the international biological NMR community.

You will be based in Prof Vuister’s structural biology research group at the University of Leicester, but there will be extensive interactions with research scientists at the various CCPN partners, which includes the national NMR facility in Birmingham as a strategic partner.

Prof Vuister is a principal member of LISCB. The Institute is superbly equipped for all aspects of X-ray, EM and NMR-based structural biology, including 600 (2x, both solid and liquid-state) and (recently upgraded) 800 MHz Bruker NMR spectrometers with cryo-probes, a Krios G3i cryo-EM, a Rigaku X-ray diffraction system, multiple robotic systems for preparing crystal screens, excellent computer facilities and a range of AKTA FPLC protein chromatography systems.  Dedicated computing facilities and senior NMR and computational experimental officers support the project.

About you

With extensive experience in either NMR spectroscopy and NMR structure determination or a relevant area of software development you must be have extensive skills and experience in programming. Experience in the dissemination of research results for publications and presentations would be desirable. 

Additional information

Part-time working would be considered. Please give details in your application. 

Informal enquiries are welcomed and should made to Professor Geerten Vuister on +44 (0)116 229 7076 or

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