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Research Associate in Developmental Cell Biology

University of Sheffield - Department of Oncology and Metabolism

Location: Sheffield
Salary: £31,302 to £33,199 per annum. Grade 7
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 21st June 2019
Closes: 21st July 2019
Job Ref: UOS023015

Contract Type: Fixed-term to start on 1 August 2019, or as soon as possible thereafter, and an end date of 31 January 2021.

Faculty: Faculty of Medicine, Dentistry and Health

Department: Department of Oncology and Metabolism

We are seeking an enthusiastic and ambitious Research Associate with a strong interest in cell and developmental biology to join the Cell Polarity and Cancer group headed by Dr Nasreen Akhtar. ( The Akhtar lab investigates the mechanisms by which epithelial tissues shape and polarize using the mammary gland as a model system. We are in the Department of Oncology and Metabolism and members of the Bateson Centre (, an internationally recognised centre of excellence with groups focussing on tissue morphogenesis.

The successful candidate will analyse the role of integrins in regulating mammary tissue morphogenesis with a particular focus on apicobasal polarity. The work will involve a broad range of cell and molecular biology techniques and the candidate will have the exciting opportunity to work with cutting edge 3D organoid co-culture technology that simulate in vivo tissues.

Applicants should have a good honours degree and hold a PhD (or be close to completion) in a relevant biological discipline (or equivalent experience). You should also have proven record of scientific accomplishments, scientific ambition, the ability to work independently and tackle scientific problems and excellent organizational and communication skills. Since the project involves the use of genetic mouse models, ASPA modular 1-3 home office training and/or a home office license will be advantageous (although outstanding candidates with other relevant skills will also be considered). Experience with molecular cloning, genetic manipulation of mammalian cells, immunofluorescence analysis and confocal imaging are essential for this post. Experience in lentiviral technology, primary tissue culture, live imaging and mouse transgenic breeding are desirable.

This full-time post is funded by the Medical Research Council.

We’re one of the best not-for-profit organisations to work for in the UK. The University’s Total Reward Package includes a competitive salary, a generous Pension Scheme and annual leave entitlement, as well as access to a range of learning and development courses to support your personal and professional development.

We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience.

To find out what makes the University of Sheffield a remarkable place to work, watch this short film:, and follow @sheffielduni and @ShefUniJobs on Twitter for more information.

This post is fixed-term to start on 1 August 2019, or as soon as possible thereafter, and an end date of 31 January 2021.

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