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Research Fellow: Understanding the mechanisms controlling receptor trafficking and localisation during synapse formation

University College London - Research Department of Cell and Developmental Biology London

Location: London
Salary: £35,328 - £42,701 per annum, inclusive of London Allowance- UCL Grade 7.
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 24th June 2019
Closes: 22nd July 2019
Job Ref: 1812871
 

Applications are invited for a Research Fellow position to study the cellular and molecular mechanisms that regulate synapse formation and plasticity in the mammalian nervous system. The successful applicant will study the mechanisms that control the trafficking and localisation of Frizzled (Fz), seven-transmembrane proteins that act as receptors for Wnt ligands during synapse assembly. The postdoctoral researcher, under the direction of Professor Patricia Salinas at UCL, will take a multidisciplinary approach that combines state-of-the-art time-lapse imaging techniques to visualise receptor trafficking in neurons, super-resolution microscopy and proteomic analyses. The researcher will also perform in vivo analyses of mutant mice using cellular and functional approaches. 

We are interested in attracting enthusiastic scientists with expertise in the following areas: cellular neurobiology, fluorescence imaging techniques, proteomic analyses and biochemistry. Experience in molecular biology and electrophysiology would be advantageous.

UCL is a world-ranking institution in the field of neuroscience that attracts students and postdocs from all over the world. UCL, located in central London, provides strong support to postdoctoral researchers with the aim to promote their career.  

The post is funded by the BBSRC for one year in the first instance with the possibility of further extension. Salary £35,328 to £42,701 per annum (Grade 7), inclusive of London Allowance.

It is essential the candidate holds a PhD (or have submitted their thesis at the time of interview) in a relevant subject area. Proven knowledge of research techniques and methodologies such as cellular neurobiology, cell imaging, and biochemistry is essential as is demonstrable comprehensive knowledge in the subject area of cellular neurobiology.

Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B (salary £30,922-£32,607 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.

UCL vacancy reference: 1812871       

Applicants should apply online. To access further details about the position and how to apply please click on the ‘Apply’ button above.

Informal enquiries should be addressed to Professor Patricia Salinas (email: p.salinas@ucl.ac.uk , telephone: 020 7679 4225).  For an outline of the lab’s research interests https://www.ucl.ac.uk/biosciences/departments/cdb/people/patricia-salinas/salinas-lab

If you have any queries regarding the application process please contact Biosciences staffing on biosciences.staffing@ucl.ac.uk quoting the vacancy reference number: 1812871.

Closing Date: 22/7/2019

Latest time for the submission of applications: 23:59.

Interview Date: TBC

UCL Taking Action for Equality

We will consider applications to work on a part-time, flexible and job share basis wherever possible.

Our department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality.

   
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