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PhD Studentship: Identification of Novel Theranostic Nanomedicine for Thrombolysis

University of Hull

Qualification Type: PhD
Location: Kingston upon Hull
Funding for: UK Students, EU Students, International Students
Funding amount: £15,009
Hours: Full Time
Placed On: 12th July 2019
Closes: 5th August 2019

To celebrate the University's research successes, the University of Hull is offering a full-time UK/EU and International PhD Scholarship for candidates applying to the following project.

Closing date: - Monday 5th August 2019

Studentships will start on 16th September 2019

Dr Simon Calaminus, Dr Graeme Stasiuk and Dr David Allsup, If you have any queries you can contact Dr Simon Calaminus on or Dr Graeme Stasiuk on

Project Description

Cardiovascular disease (CVD) is a leading cause of death worldwide. Critical to CVD is the blood cell, the platelet as excessive activation of this cell can lead to occlusive thrombi, causing stroke. Although it is possible to targeting thrombi in patients with thrombolytic drugs, this therapy has significant risk of serious side-effects.  Therefore there is a need to produce more targeted and effective treatment.

This PhD sets out to validate and understand a series of state of the art therapeutic imaging nanomedicines or ‘theranostic’ agents for advancing targeted and personalised therapy in stroke patients. The development of nanomaterials for this purpose is an important strategy for achieving critical advances in diagnostic medical imaging and drug delivery. This will involve studying platelet activation pathways in in vitro models such as platelet aggregation and in vitro flow and how these are affected by the synthesised theranostics.

The successful candidate will be expected to have a 2:1 undergraduate degree in biomedical sciences, medicine, natural sciences or an equivalent degree, with a willingness to learn in vitro platelet biology and imaging studies. International students can apply, although will need to also provide the relevant IELTS.

This is a PhD studentship is funded by the University of Hull as part of a larger Medical Research Council (MRC) funded research project within Dr Graeme Stasiuk’s (biomedical sciences), and Dr Simon Calaminus (Hull York medical School) research groups.

To apply for these Scholarships please click on the Apply button below.

Full-time UK/EU and International PhD Scholarships will include tuition fees and maintenance (£15,009 in 2019/20) for three years, depending on satisfactory progress.

PhD students at the University of Hull follow modules for research and transferable skills development and gain a Masters level Certificate, or Diploma, in Research Training, in addition to their research degree.

Successful applicants will be informed of the award as soon as possible and by 30th August 2019 at the latest.

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