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Research Fellow

UCL - Division of Infection and Immunity

Location: London
Salary: £35,965 to £43,470 Per annum, inclusive of London Allowance
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 26th March 2020
Closes: 26th April 2020
Job Ref: 1864918
 

Applications are invited for a Postdoctoral Research Fellow position in the Division of Infection and Immunity in the laboratory of Professor Arne Akbar. The post is funded by a 3 year grant from the Leo Foundation awarded to Professor Akbar.

The title of the project is: "Mechanisms involved in decreased cutaneous immunity during ageing: reversal by Vitamin D pre-treatment".

The successful candidate will join a group of basic and clinical scientists all working on integrated aspects of immunosenescence; the reduction in immune function with advancing age. The main focus of the Akbar lab is the study of effects of ageing on the human immune system. By identifying changes in immune function and the mechanisms behind these alterations, the research group aims to accelerate the development of new immune enhancing therapies for older adults. Akbar group has developed and validated a new model for the study of a human memory T cell response in the skin in vivo and is currently using this model to investigate the causes for defective secondary responses to antigen injection in the skin of older humans. Professor Akbar has a number of leading national and international collaborators. For further details on the lab please see: https://twitter.com/AkbarLab

The post-holder will work closely with a collaborator at Queen Mary's University of London, Dr Emma Chambers, who has extensive experience with the immune modulatory role of Vitamin D. This study will increase the platform of knowledge on the regulation of T cell dysfunction during human ageing. The Akbar group is at the forefront of such studies worldwide.

The position is funded until 31st March 2023 in the first instance.

Candidates should have a PhD or equivalent in Biochemistry/Immunology/ Biomedical Sciences or a related subject, or have equivalent working experience. Competency in sterile cell culture and multiparameter flow cytometry as well as experience in T cell subset isolation, antigen specific techniques, immunohistochemistry/immunofluorescence are essential requirements.

Note: Appointment at grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B (salary £31,479 - £33,194 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.

Applicants should apply online. To access further details about the position and how to apply please click on the ‘Apply’ button above.

If you have any queries regarding the application process, please contact Isabel Lubeiro by email at i.lubeiro@ucl.ac.uk .

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