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Postdoctoral Fellow - Birney Research

European Molecular Biology Laboratory (EMBL)

Location: Cambridge, Hinxton
Salary: £2,829.64 (Year 1 Stipend)
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 1st October 2020
Closes: 6th November 2020
Job Ref: EBI01709

About the team/job

We are looking for a post-doctoral fellow with a strong computational background and interest in quantitative trait analysis to join the Birney research group at EMBL-EBI to work on a new ERC funded project in collaboration with the University of Heidelberg - IndiGene.

Over the last seven years dedicated work has led to the establishment of the first near isogenic panel in vertebrates, the inbred medaka MIKK panel. The IndiGene project will make use of this new valuable resource to separate various sources of phenotypic variation, primarily genetic variation, environmental variation and stochastic variation.

Your role

A major part of this work is the analysis of complex phenotyping measurements for genetic association testing. The optimization and/or development of reliable image processing methods for extracting robust measurements from high resolution, complex imaging datasets will be required. These imaging assay types include: CT-scans of whole adult fish, high-resolution/high-throughput embryo imaging and complex free-swimming videos. There will also be a need for detailed experimental protocols to be designed and agreed with laboratory staff, maintaining the essential link between experimental work and computational analysis. Developing well planned experimental designs for large-scale phenotyping assays and analysis is an important part of the role.

You have

  • PhD in Bioinformatics, Physics, Computer Science, or related fields and will have a proven track record in computational data analysis.
  • You should be skilled at developing software in a Unix-based environment as well as having an awareness of good computational practices and experimental design.

You might also have

Knowledge of current machine learning based methods would be beneficial. Experience in database design and implementation is not required but would be considered as an advantage.

The successful applicant will be part of a highly collaborative team working between groups at EMBL-EBI and the University of Heidelberg. There will be regular project meetings and interaction with both computational and laboratory staff so the ability to present results and discuss ideas; good interpersonal skills will be beneficial. There will also be the opportunity to take part in a number of field trips to  Japan to help design and setup phenotyping assays on wild medaka fish.

What else you need to know

To apply please submit a covering letter and CV through our online system. At EMBL-EBI, we strongly believe that inclusive and diverse teams benefit from higher levels of innovation and creative thought. We encourage applications from women, LGBTQ and individuals from all nationalities. Applications are encouraged from all nationalities and this has continued after Brexit. For more information please see our website. Visa information will be discussed in more depth with applicants selected for interview.

This position is limited to a 3 year duration in the first instance. Applications will close at 23:00 GMT on the date listed above.

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