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2 PhD Studentships/Marie Sklodowska-Curie ESRs: Rational Design of Antibodies

University of Cambridge - Yusuf Hamied Department of Chemistry

Qualification Type: PhD
Location: Cambridge
Funding for: UK Students, EU Students, International Students
Funding amount: see advert text.
Hours: Full Time
Placed On: 23rd February 2021
Closes: 31st March 2021
Reference: MA25789

Fixed-term: The funds for these posts are available for 3 years.

We invite applications for two Marie Sklodowska-Curie Early Stage Researcher (MSC-ESR) Fellowships, starting 1 October 2021, to work with Professor Michele Vendruscolo in the Centre for Misfolding Diseases on the development of fragment-based computational design methods for antibody discovery.  The specific goals are:

  1. To review and finalise the selection of relevant target antigens; 2. To apply the rational antibody discovery approach to design novel antibodies against these antigens; 3. To express and purify the novel antibodies, and test their affinity and specificity for their targets.

The project will form part of a EC Marie Sklodowska-Curie European Training Network (Bio2Brain), which unites 11 academic teams, 5 key industrial stakeholders and an academic non-profit organisation from across Europe.  Although based in Cambridge, the successful candidate will have the opportunity to collaborate with different members of the network, including secondments, yearly summer schools and attendance at international meetings.

More information about the Bio2Brain network can be found at: https://bio2brain.eu

More information about the research in the Vendruscolo group can be found at:  https://www.ch.cam.ac.uk/person/mv245

https://www.cmd.ch.cam.ac.uk/

Applicants must satisfy the EC's eligibility requirements for MSC-ESR Fellowships, and must not have resided in the UK for more than 12 months in the last three years. Candidates should have (or expect to obtain) at least the equivalent of a UK upper second class honours degree (and preferably a Masters degree) in physics, chemistry, computer science, molecular biology, or other relevant scientific discipline. Candidates should have an interest in computational physics, computational chemistry or bioinformatics. Basic knowledge of bio-analytics would be desirable.

The Fellowship is offered in conjunction with a PhD position, subject to the Fellow satisfying the university's admissions requirements for PhD study. The Fellowship will provide a salary that includes a living allowance of around €40,000 p.a. plus a mobility allowance of around €6,425 p.a..

Applications should include a CV, a half-page summary of master/diploma thesis, certificates of examination grades, a cover letter (up to 1 page) describing your research career goals, skills and experience, and contact details for at least two academic referees, and should be sent by email to Professor Michele Vendruscolo (mv245@cam.ac.uk). Informal enquiries about the positions can also be addressed to Professor Vendruscolo.

Please quote reference MA25789 on your application and in any correspondence about this vacancy.

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