|Salary:||£35,845 to £40,322 per annum|
|Placed On:||22nd July 2021|
|Closes:||20th August 2021|
We are seeking one or two talented postdoctoral Research Associates to work with Professor Robert Insall’s lab at the Institute of Cancer Sciences, Glasgow from 1st November 2021. The project is funded by an Investigator award from the Wellcome Trust, to study chemotaxis to self-generated gradients. The work is highly interdisciplinary, involving technical microscopy, immunology, mathematical and computational modelling and microfluidics. We will study how cells create their own gradients of chemoattractants, and how this mechanism affects a wide range of biological processes. We are particularly interested in lymph nodes, so applicants with experience in T cell or dendritic cell biology would be welcomed, but also study neutrophil extravasation and reverse chemotaxis, and mechanisms of gradient formation using Dictyostelium.
We recently discovered that cells can use self-generated chemotactic gradients to explore their environments and choose paths, even solving complex microfluidic mazes (Tweedy et al. (2020) Seeing around corners: Cells solve mazes and respond at a distance using attractant breakdown. Science 369:eaay9792). The aim of this project is to extend these findings, both theoretically and to a wider range of physiological conditions, for example T cells and dendritic cells in lymph nodes.
Successful candidates will have a PhD. and/or M.D. degree, and a good record of achievement. Candidates with expertise in any of the following fields will be favoured: immune cell biology; technical microscopy; analysis of cell migration; coding; computational modelling; and soft lithography. We are looking for candidates who are interested in pursuing multidisciplinary research.
Professor Insall’s group is split between the Cancer Research UK Beatson Institute and the University of Glasgow Institute of Cancer Sciences. Both are in the Garscube Campus in Bearsden, which offers a superb environment combining modern, high quality laboratories and infrastructure with abundant free space, recreational and sporting facilities.
These posts are full time (35 hours) with funding until October 2026.
For informal enquiries, please contact Professor Robert Insall, Robert.Insall@glasgow.ac.uk
Closing date: 20th August 2021
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