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Faculty Positions - Cancer, Ageing and Somatic Mutation

Wellcome Sanger Institute

Full Time/Flexible working considered

Contract Type: Various

The Wellcome Sanger Institute is seeking two exceptional early to mid-career stage scientists to join its Core Faculty to lead a research team in Cancer, Ageing and Somatic Mutation and contribute to the Institute’s scientific portfolio. Positions carry a significant core package of salaries and support backed by rewarding and flexible employment terms including excellent benefits and relocation support. 

Faculty positions in Cancer, Ageing and Somatic Mutation

The Cancer, Ageing and Somatic Mutation programme comprises two major themes: (1) Genome sequencing to study somatic mutations in normal tissues, their causes, their consequences on disease and ageing phenotypes and how they vary across different organs, different individuals and different species; and (2) cellular and mouse models to study how mutations in cancer genes alter cell viability, unmask dependencies on essential genes and influence clonal dynamics and response to environmental stressors.

The Cancer, Ageing and Somatic Mutation Programme explores basic scientific questions about the role somatic mutation plays in clonal evolution, ageing and development, develops high-throughput cellular models of cancer for genome-wide functional screens and drug testing and provides leadership in data aggregation and informatics innovation.

For more information about the programme and its team, visit

Support available in Cancer, Ageing and Somatic Mutation

We have an established core operations infrastructure to support the research of the Programme. The Operational teams, led by the Head of Cancer, Ageing and Somatic Mutation Operations, are structured into three primary areas:

  • Wet-lab core team,
  • Informatics team,
  • Administration team.

These teams work collaboratively to deliver a backbone of operational support to the Cancer, Ageing and Somatic Mutation Programme Faculty, enabling them to focus on delivering their cutting-edge research.

The operations teams also provide a key interface with central Institute functions including the core Sanger pipelines within Scientific Operations and the Management Operations teams. The Administration team provides day-to-day administration including core and grant funding finance management, identifying third party funding opportunities, and ensuring regulatory and legal compliance in collaboration with central Institute teams.

Roles available in Research Programme

Cancer, Ageing and Somatic Mutation is seeking an exceptional GL1 and GL2 scientists to join as Core Faculty members leading a research team, and contributing to the Institute’s scientific portfolio. Positions carry a significant core package of salaries and support, which are backed by rewarding and flexible employment terms including excellent benefits and relocation support. Our exceptional core funding enables Faculty to focus their energy on science.

Our Levels of Faculty are:

Group Leader 1 (GL1)

GL1 Faculty positions are designed to be a researcher’s first or second group leader role and are the equivalent of a Lecturer at a UK University or Assistant Professor at a US University. They are focused on developing new and complementary areas of research within a Programme, and individuals at this level will have already contributed to research in an independent, original, and significant way with a strong trajectory and developing publication record. They should have an understanding and have contributed to the development and delivery of a coherent Programme strategy, and will have built up networks of research contacts and be confident in giving findings at conferences. Forward planning the work of their own group including how they will mentor and motivate their line reports must also be present. These positions are six year posts.

Group Leader 2 (GL2)

During the course of their tenure, these Faculty roles become equivalent of an Associate Professor and are intended to provide opportunities to develop an internationally competitive research portfolio and will have a track record of scientific publication, evidence of external recognition and other outputs leading to scientific impact and advancement of their discipline nationally and/or internationally. They will be able to reflect on and influence the Programme strategy; contributing to its development and delivery, coherence and agility. They will be able to show effective management of a research team, including planning at a larger scale and higher level of complexity. This will include leadership of a team including the development, proactive mentoring and motivation of colleagues and line reports. These positions are for eight years with a promotional review during the sixth year.

For further information about our Faculty Model, please visit

Opportunity and selection criteria

Cancer, Ageing and Somatic Mutation seek Faculty with research interests in any (or a combination) of the following:

  • Cancer genomics
  • Somatic mutation analysis
  • High-throughput model systems
  • Computational biology
  • Genome editing

Candidates will be considered across the GL1 and GL2 Faculty levels and in assessing the best qualified applicants, we will focus on scientific achievement, experience, leadership and personal suitability in line with our core behavioural competencies; collaboration, communication, leadership, integrity, results-driven, and innovation.

About the Institute

The Wellcome Sanger Institute is a world-leading genomics research centre, based on the Wellcome Genome Campus, one of the largest single-site communities worldwide of expertise in Genomes and BioData. We undertake large-scale research that forms the foundations of knowledge in biology and medicine. We are open and collaborative; our data, results, tools and technologies are shared across the globe to advance science.

Our ambition is vast – we take on projects that are not possible anywhere else.

The high-throughput, large-scale biological research undertaken at the Institute is a central defining characteristic distinguishing our science from that of most research institutes and universities.

It’s an exciting time to join the Sanger Institute as we recruit exceptional scientists in all five of our research programmes: Cancer, Ageing and Somatic MutationCellular GeneticsHuman GeneticsParasites and Microbes, and Tree of Life, spanning all levels of our Faculty model. You’ll join a unique, vibrant and interactive research environment with an internationally outstanding genomic research centre at the heart, as a Core Faculty member to lead a research team in one of the five programmes, and contribute to the Institute’s scientific portfolio.

Other information

Application Process:

Applications should be accompanied by:

  • Curriculum vitae, complete list of publications and details of three referees;
  • A two-page cover letter summarising:
  • your scientific and leadership achievements to date,
  • your contribution to the wider research community and society, you may wish to include diversity and inclusion initiatives and public engagement events.
  • which Faculty level you wish to be considered for and why; and                          
  • A three-page outline of future research plans indicating how these fit with the research areas, the chosen Programme, and the wider Institute. Please include a short abstract at the start of this document (no more than 250 words) summarising your plans. 

We understand that the global impact of COVID-19 and the lockdown period may have negatively impacted your research, as you may have had to adjust your working pattern, had reduced access to research facilities, and/or taken on additional responsibilities, such as childcare or caring for others. As part of our recruitment process we would like to better understand your experiences and how COVID-19 has impacted on your research progress and any research outputs, so that we can take this into consideration when we review your application. Please use the application form to tell us more.

Interviews will be held in January/February 2022

For an informal conversation about the positions in Cancer, Ageing and Somatic Mutation, please contact Dr Peter Campbell. Further information regarding the Institutes science, Faculty and building a career at the Institute can be found at Our ScienceFaculty teams and Faculty careers

If you have any questions about the application process or have any informal enquiries about working at and moving to the Sanger Institute, please contact Sam Bowker, Head of Recruitment and Immigration.

The Sanger Institute is an Equal Opportunity employer. We aim to attract, recruit, retain and develop talent from the widest possible talent pool, thereby gaining insight and access to different markets to generate a greater impact on the world. Our global reputation for excellence is strengthened by our commitment to developing and maintaining an organisation where staff from all backgrounds can thrive.

Location: Cambridge, Hinxton
Salary: Grade: Faculty Level 1/2
Hours: Full Time
Contract Type: Permanent
Placed On: 20th August 2021
Closes: 31st October 2021
Job Ref: 84416
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