NDORMS, Kennedy Institute of Rheumatology, Old Road Campus, Oxford, OX3 7FY
Grade 7: £33,309 – £40,927 p.a.
We have an exciting opportunity within the Genomics of Inflammation laboratory at the Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS). The post holder will have responsibility for carrying out research in the transcriptional and molecular control of neutrophil development and function in inflammatory tissue microenvironment, within a new leading-edge programme funded by the Wellcome Trust (see Khoyratty et al, Nature Immunology 2021; Ballesteros et al, Cell 2020). You will be using unique in vivo models, advanced immunological and imaging approaches and innovative single cell technologies to study how neutrophil function in the tissue is guided by intrinsic molecular regulators and influenced by extrinsic protein and lipid signals produced by macrophages.
As a Postdoctoral Researcher in Innate Immunity and Inflammation you will take responsibility for the planning and execution of high quality research, ensuring the validity and reliability of data at all times, as well as test hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate. You will also contribute ideas for new research projects, co-ordinate multiple aspects of work to meet deadlines, and provide guidance and support to PhD students and other members of the group.
You will hold a PhD (or near completion) in immunology, molecular and cellular biology, or similar, and have excellent communication skills, including the ability to write for publication, present research proposals and results, and represent the research group at meetings. You will demonstrate capacity to deliver high quality research outputs, illustrated by a strong publication record in high profile immunological journals, as well as possess sufficient specialist knowledge in transcriptional control of immune cell development and function to work within established research programmes. Expertise in neutrophil biology, functional and single cell genomics, spatial transcriptomics or advanced imaging analysis would be desirable.
This is a full-time appointment fixed-term until 24/06/2024.
You will be required to upload a supporting statement, CV and names of referees as part of your online application.
The closing date for applications is 9am on Monday 27 September 2021.
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