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Senior Scientific Officer

The Beatson Institute for Cancer Research - McNab Centre

Location: Glasgow
Salary: £33,000 to £43,000 dependent on experience
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 13th September 2021
Closes: 10th October 2021

McNab Centre for Cancer Innovation - supported by a generous bequest from Annie McNab

One of the main challenges that we face in treating cancer is the likelihood that, at the time of diagnosis, malignant cells have already left the primary tumour and spread to other organs. Thus, even following complete removal of the primary tumour, disseminated cells can reside within ‘metastatic niches’ only to reappear later as metastasis.

A substantial donation from Ms Annie McNab to the CRUK Beatson Institute has enabled us to establish a new Centre for Cancer Innovation in Glasgow to address this significant challenge to effective cancer treatment. The McNab Centre for Cancer Innovation, which is led by Profs. Ross Cagan, Jim Norman and Dr Chiara Braconi, is a laboratory that focuses on the development and application of new technologies to identify and target the vulnerabilities of cancers once they have spread from the primary site to a metastatic one. We are developing bioengineered human tissues and other technologies—including mouse and Drosophila models—to recapitulate the microenvironments that are encountered in the liver, bone, and lungs by metastatic cancers. We will combine these approaches with state-of-the-art screening and chemical evolution to develop new leads for drugs to treat metastasis to these organs.

We welcome applications from bright and ambitious scientists for the following position that has recently become available within the McNab Centre, which will be based in the Institute of Cancer Sciences and CRUK Beatson Institute, Glasgow.

Senior Scientific Officer

We seek a scientist/laboratory manager with excellent collaborative and project management skills to provide day to day management of the McNab Centre of Cancer Innovation. The successful applicant will be responsible for working in collaboration with colleagues in the McNab Centre (including the Directors, Post-docs, PhD students and their supervisors) to establish and run technologies that interrogate vulnerabilities of cancer cells in metastatic microenvironments. Technologies will include use of patient-derived primary tumour and metastatic organoids, bioengineered reconstructions of the liver, lung and bone microenvironments, robotics, and high-content screening. Responsibilities will also include working alongside the Beatson Institute’s Finance and Laboratory Operations teams to plan and run the McNab Centre laboratory and to manage its budget.

A relevant PhD and post-doctoral experience in cell biology/immunology, organoid approaches and/or advanced imaging techniques would be an advantage.

Informal enquiries should be directed to Prof. Ross Cagan (ross.cagan@glasgow.ac.uk), Prof. Jim Norman (j.norman@beatson.gla.ac.uk) and Dr Chiara Braconi (chiara.braconi@glasgow.ac.uk).

All applications must be made via our website  https://www.beatson.gla.ac.uk/The-McNab-Centre-for-Cancer-Innovation/mcnab.html

Closing date for applications 10th October 2021

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