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Research Associate

Imperial College London - Section of Hepatology & Gastroenterology

Location: London
Salary: £41,593 to £49,210 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 13th September 2021
Closes: 1st October 2021
Job Ref: MED02675
 

Location: Hammersmith Campus (East Acton)

Department: Section of Hepatology & Gastroenterology, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine

Job Summary:

A Research Associate post is available within the Antigen Presentation Research Group (APRG), part of the Department of Metabolism, Digestion and Reproduction at Imperial College, Hammersmith Campus. The interests of the section are in human mucosal immunology and its relationship with the gut microbiota and lipid metabolism/nutrition. This ongoing project is part of the Gut Health and Food Safety (GHFS) Strategic Research Programme in collaboration with the Quadram Institute Bioscience (QIB), Norwich, funded by BBSRC, providing a platform to examine immunological aspects relevant to maintaining a healthy human gut.

Duties and Responsibilities:

You will help define mechanisms of self/non-self-discrimination in the healthy human intestine and the influence that mucosal immune cells, particularly dendritic antigen-presenting cells have on homeostasis in the gut through their interactions with the microbiota and host metabolism. Thus, the effects of different components of the normal microbiota on dendritic cell subsets, morphology, activation-/differentiation, cytokine production, migratory potential and functional capacity as antigen-presenting cells will be defined. Secondly the links between mucosal immunity and metabolism (immunometabolism) will be defined from immune cell fat uptake and induced functional changes that impact on host immunity, metabolism and obesity. This programme utilises established collaboration for studying human immunology between the APRG and St Mark’s Hospital and Research Institute for Colorectal Diseases. 

Essential Requirements:

Key requirements include a PhD in immunology, microbiology, nutrition or a related discipline and experience in human immunology and flow cytometry; knowledge of cell biological techniques and/or nutrition. Ability to design and conduct experiments, as well as excellent written communication skills and the ability to write clearly and succinctly for publication. Experience of providing guidance and supervision in laboratory-based research to students (PhD/MD) and junior members of the laboratory is essential.

Further Information:

This role is offered on a full time and fixed term basis until 31 March 2022 with potential to extend, subject to funding.

Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £36,694 - £39,888 per annum.

For any further information please contact Professor Stella Knight at s.knight@imperial.ac.uk

The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/

We are committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment for all. We therefore encourage candidates to apply irrespective of age, disability, marriage or civil partnership status, pregnancy or maternity, race, religion and belief, gender identity, sex, or sexual orientation. We are an Athena SWAN Silver Award winner, a Disability Confident Leader and a Stonewall Diversity Champion.

Closing date: 01 October 2021

To apply, visit www.imperial.ac.uk/jobs and search by the job reference MED02675.

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