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Postdoctoral Researcher - DNA Damage Imaging

University of Oxford - Department of Oncology

Location: Oxford
Salary: £33,309 to £37,467 per annum (up to first 5 points on scale available). Grade 7
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 6th October 2021
Closes: 29th October 2021
Job Ref: 153625

Location: Department of Oncology, Radiobiology Research Institute, Churchill Hospital, Headington, Oxford, OX3 7LJ

Salary: Grade 7: £33,309 - £37,467 per annum (up to first 5 points on scale available) 

We have a new opportunity for a highly motivated and enthusiastic Postdoctoral Researcher to contribute to the research of the Radiopharmacy and Molecular Imaging Group, led by Dr Bart Cornelissen. This is an exciting research programme, funded by Prostate Cancer Research, in seeking to improve 177Lu-PSMA therapies by evaluating promising drug combinations in vitro and in preclinical models of prostate cancer.

You will undertake research into DNA damage repair modulation following radionuclide therapy with 177Lu-PSMA in prostate cancer models. The project involves in vitro and in vivo studies using tumour-bearing animals and you will be responsible for managing your own research and administrative activities. The role will include coordination of experiments, assisting with the supervision of students and generation of high quality data suitable for publication and for submission in the context of grant proposals. You will also present results and discuss scientific findings at national and international meetings.

You will hold (or be very near to completing) a PhD in cancer biology, molecular biology or related discipline and have expertise in molecular biology (RNA sequencing) and pathway analysis. You will have the ability to work independently and in collaboration with external research groups. Experience or willingness to handle open-source radiation safely is essential. A Home Office personal licence (PIL) and previous experience with the CRISPR/Cas9 system and radiation biology would be advantageous.

This is a full-time post, fixed term for 18 months in the first instance. An early start date is essential.

The post will be based at the Radiobiology Research Institute, Churchill Hospital, Headington, Oxford, OX3 7LJ.

All applicants must complete a short application form and upload a CV and supporting statement. 

The closing date for applications is 12.00 noon on Friday 29 October 2021.

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