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Postdoctoral Research Associate in Hematopoietic Stem Cell Biology

Imperial College London

Location: London
Salary: £41,593 to £49,210 p.a. plus benefits
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 12th November 2021
Closes: 12th December 2021
Job Ref: NAT01011
 

We are seeking to recruit an outstanding Research Associate, that is passionate about haematopoietic stem cells and their interactions with the bone marrow microenvironment. You will join the Haematopoietic Stem Cells Laboratory, led by Dr Tiago C. Luis at South Kensington Campus.

The Luis lab focuses on understanding the molecular mechanisms by which the bone marrow niche regulates haematopoietic stem cells (HSC) function in the maintenance of blood cells homeostasis and the development of haematological malignancies. You will work on an exciting project aiming at understanding how myeloid leukaemia remodels the HSC niche to favour leukaemia development. This is a multidisciplinary project based on transgenic mouse models of leukaemia development, which will be analysed by multi-parameter flow cytometry, RNA sequencing, imaging and computational/systems biology methods. For more details on our research please visit our laboratory web site.

Duties and responsibilities

You will drive the research project and will be responsible for independently running experiments and day-to-day project management and development. The project will involve a high degree of teamwork, interdisciplinary research and flexibility in developing and managing complex and demanding experimental protocols and data sets. Your main duties are described below:

Main duties:

  • To be pro-active in planning and conducting the research work and to perform data analysis, with appropriate supervision
  • To ensure the validity and reliability of data at all times
  • To perform research that fulfils the requirements of the grant objective
  • To present findings to colleagues, collaborators and at conferences, in a logic and structured way
  • To draft publications and prepare them for submission to peer reviewed journals

Essential requirements

You must hold a PhD (or equivalent research, industrial or commercial experience) in haematology, immunology, stem cell biology or a closely related discipline

You must be able to demonstrate:

Experience with:

  • In vivo mouse models
  • Flow Cytometry
  • Gene expression analysis such as RNA sequencing 

Knowledge of:

  • Stem cell biology and/or haematopoiesis
  • Research methods and data/statistical analysis in these fields

Experience in Bioinformatics and imaging will be an asset.

Further information

This is a full time, fixed term position until 31 October 2023, with possible extension depending on funding availability. You will be based at South Kensington Campus.

Candidates who have not yet been officially awarded their PhD will be appointed as Research Assistant within the salary range £36,694 – £39,888 per annum.

For more information visit the laboratory web site.

Should you require any further details on the role please contact Dr Tiago Luis (t.luis@imperial.ac.uk).

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