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PhD Studentship: Bacteriophages as Precision Medicine in the Ageing Gut

University of East Anglia - Quadram Institute Bioscience

Qualification Type: PhD
Location: Norwich
Funding for: UK Students, EU Students, International Students
Funding amount: See advert details
Hours: Full Time
Placed On: 25th November 2021
Closes: 17th January 2022
Reference: ADRIAENSSENS_Q22MMB

Bacteriophages are the most abundant biological entity on the planet, but their role in the human microbiome is poorly understood. In this project, the student will use a combination of viromics and culturing to investigate the bacteriophages in the gut of an elderly patient cohort. The student will use our state-of-the-art model systems mimicking the human gut to develop interventional strategies to treat dysbiosis.

We are recruiting a student on an MRC-funded project at the Quadram Institute Bioscience in the area of Gut Microbes & Health. The student will join the group of Dr Evelien Adriaenssens, expert in bacteriophages and viromics, in collaboration with Prof Simon Carding (gut microbiome interactions in health and disease) and Dr Falk Hildebrand (bioinformatics approaches to personalised microbiota care).

The ideal candidate has at a minimum an Upper Second Class Honours degree in Microbiology, Biotechnology or Bioinformatics (or equivalent) and a passion for research. Since this project combines both microbiology and bioinformatics approaches, we will consider appropriate expertise in either microbiology or bioinformatics with the desire to learn about the other aspects. The willingness to learn advanced skills in bioinformatics including the use of the command-line is essential.

The PhD student will be based in the new purpose-built Quadram Institute building located on the Norwich Research Park, where they will join a vibrant research community at the interface between fundamental and translational research into gut microbiology. The QIB offers a wide range of training opportunities, laboratory and computational scientific support and funding to attend conferences, preparing the student for any career of their choice.

The Microbes, Microbiomes and Bioinformatics (MMB) Doctoral Training Partnership (DTP) is open to UK and international candidates with an undergraduate degree relevant to the scope of the programme for entry in October 2022 and offers postgraduates the opportunity to undertake a 4-year PhD research project funded by the UKRI Medical Research Council to advance the training of students in microbiology, with an emphasis on microbial bioinformatics.

This project has been shortlisted for funding by the MMB DTP programme. Interviews for shortlisted candidates will take place on Tuesday 15 or Wednesday 16 February 2022.

This MMB DTP is committed to equality, diversity, widening participation and inclusion in all areas of the programme. We encourage enquiries and applications from all sections of the community, regardless of gender, ethnicity, disability, age, sexual orientation, and transgender status. We value an aptitude for computer-based analysis, curiosity, and independence of thought, plus a commitment to work across the boundaries between the laboratory and bioinformatics to deliver high-impact research. We welcome applicants from low- and middle-income countries.

For information on eligibility and how to apply: https://www.uea.ac.uk/research/research-with-us/postgraduate-research/latest-phds-and-research-studentships/partnerships-in-doctoral-training

Primary Supervisor :  Dr Evelien Adriaenssens

Start date: October 2022

For more information on this project, please visit http://www.uea.ac.uk

This project is awarded with a 4-year MMB DTP PhD studentship, which includes support for a maintenance stipend, provided over four years, full tuition fees and research and training costs.

Studentship funding will not normally cover costs associated with visa or health surcharges, or additional costs associated with entry to, and living in the UK.

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