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Bioinformatics Developer

European Molecular Biology Laboratory (EMBL) - Genes, Genomes & Variation

About the team/job

In the Variation team, we integrate and annotate large quantities of variation data from public archives and develop tools for data access, visualisation and variant interpretation. The Ensembl Variant Effect Predictor (VEP), which leverages a wide range of data to create detailed variant annotations, is our most popular product.

We seek a talented, highly motivated bioinformatics developer to help adapt and optimise our variation tools, pipelines and resources to utilise this new reference and make pangenome data available to the community. 

Your role

Main Duties and Responsibilities

Your primary responsibilities will include:

  • Developing and maintaining efficient methods for large-scale variant data management
  • Developing and maintaining tools for the functional annotation of variants
  • Investigating and integrating new data formats and tools
  • Collaborating with members of the broader Ensembl team both on specific development projects and to coordinate regular data/software releases
  • Engaging with the HPRC to understand tool availability and data quality
  • Sharing our work at internal meetings and scientific conferences and engaging with our user community to provide support and understand their needs

This position offers the motivated candidate a unique opportunity for significant scientific involvement with other groups at the EMBL-EBI beyond. 

You have

  • Bachelors (or equivalent) degree in computational or biological sciences
  • Higher degree or equivalent experience in genetics, biological or computational sciences
  • Experience of working with genomics data, preferably sequence variation data
  • Experience working to deadlines while delivering a high-quality product in a production development environment
  • High proficiency working in a UNIX/Linux environment
  • Proficiency in at least one programming language, preferably with knowledge of Python or Perl
  • Excellent communication, interpersonal and English language skills
  • Clear and accurate technical communication
  • A professional and helpful manner including when responding to support requests
  • Ability to work closely with other team members, giving and receiving constructive feedback
  • Ability to collaborate with colleagues from different disciplines
  • Good attention to detail
  • High motivation, scientific curiosity and initiative 

You might also have

experience to demonstrate your ability to:

  • Design and develop efficient large-scale data analysis pipelines and user-friendly tools/APIs
  • Focus on efficient and professional service provision
  • Use and understand the Ensembl APIs and services
  • Use and be familiar with standard bioinformatics software and formats, particularly for genome alignment and variant discovery.
  • Use relational database systems
  • Employ robust testing strategies
  • Work on a shared codebase using version control systems, preferably Git.
  • Present work on behalf of the group at meetings and conferences 

Why join us

Do something meaningful
At EMBL-EBI you can apply your talent and passion to accelerate science and tackle some of humankind's greatest challenges. EMBL-EBI, part of the European Molecular Biology Laboratory, is a worldwide leader in the storage, analysis and dissemination of large biological datasets. We provide the global research community with access to publicly available databases and tools which are crucial for the advancement of healthcare, food security, and biodiversity.

Join a culture of innovation
We are located on the Wellcome Genome Campus, alongside other prominent research and biotech organisations, and surrounded by beautiful Cambridgeshire countryside. This is a highly collaborative and inclusive community where our employees enjoy a relaxed atmosphere. We are committed to ensuring our employees feel valued, supported and empowered to reach their professional potential. 

Enjoy lots of benefits:

  • Financial incentives: Monthly family, child and non-resident allowances, annual salary review, pension scheme including 17% employer contribution, death benefit, long-term care, accident-at-work and unemployment insurances
  • Flexible working arrangements
  • Private medical insurance for you and your immediate family (including all prescriptions and generous dental & optical cover)
  • Generous time off: 30 days annual leave per year, in addition to eight bank holidays
  • Relocation package including installation grant (if applicable)
  • Campus life: Free shuttle bus to and from work, on-site library, subsidised on-site gym and cafeteria, casual dress code, extensive sports and social club activities (on campus and remotely)
  • Family benefits: On-site nursery, child sick leave, generous parental leave, holiday clubs on campus and monthly family and child allowances
  • Benefits for non-UK residents: Visa exemption, education grant for private schooling, financial support to travel back to your home country every second year and a monthly non-resident allowance.

For more details please see our employee benefits page.  

What else you need to know

  • Contract duration: This is a grant based position and will end by July 2024
  • International applicants: We recruit internationally and successful candidates are offered visa exemptions. Read more on our page for international applicants
  • Diversity and inclusion: At EMBL-EBI, we strongly believe that inclusive and diverse teams benefit from higher levels of innovation and creative thought. We encourage applications from women, LGBTQ+ and individuals from all nationalities. 
  • Job location: This role is based in Hinxton, UK and you will be required to relocate once it is safe to do so, if you are currently based abroad. Read more about how we are recruiting during the pandemic.
  • Your application: To apply please submit a cover letter and a CV through our online system.
Location: Hinxton
Salary: Grade 5 or 6 (starts at £2,809 or £3,143 per month after tax) + other paid benefits
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 13th January 2022
Closes: 24th February 2022
Job Ref: EBI01970
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