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Postdoctoral Training Fellow - Systems and Precision Medicine Team

The Institute of Cancer Research

Location: Sutton
Salary: £38,607 to £45,224
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 14th January 2022
Closes: 8th February 2022
Job Ref: ID:87

Key Information

Salary: Starting salary £38,607 - £40,902

The full salary range for the grade is £38,607 - £45,224. Starting salary dependent on relevant postdoctoral experience. Future progression is based on annual performance review., future progression is based on annual performance review. If the candidate has not yet been awarded their PhD, the starting salary will be  at £32,844 until the successful completion of their viva.

Duration of Contract: Fixed Term for 1 year

Hours per week: 35 (Full Time)

Job Details

Research LeadDr Anguraj Sadanandam

Summary of Role

As Postdoctoral Training Fellow you will be required to help us to characterize biomarkers identified in colorectal cancer primarily using patient samples and in vivo and in vitro models. You will also be involved in testing subtype-specific therapies using pre-clinical trials and will enjoy working in the interdisciplinary fields and collaborating with our internal and external collaborators.

Key Requirements

We are looking for a highly motivated and well-organised individual with a great attention to detail and strong analytical skills and will also have experience in patient samples handling and mechanism based research. Your responsibilities will include day-to-day laboratory operations such as cell culture, different molecular biology and biochemical techniques (including, but not limited to DNA, RNA and protein isolation, isolation, RT-PCR, Western blots, immunohistochemistry, methylation PCR, CHIP assays, basic bioinformatics and in vitro and in vivo experiments and interpretation of the results. In addition, you will work closely with the team and other collaborators to develop and validate hypothesis that will arise out of the high-throughput omics data including genomics and metabolomics.

The successful applicant will hold a PhD in molecular medicine or cancer biology. Experience in handling patient tumour tissues, laboratory management, molecular biology and biochemical techniques, cell culture and in vivo experiments is essential as well as excellent organizational, scientific writing and communication skills. Experience in statistical data analysis and computational biology/bioinformatics would be advantageous.

The ICR has a workforce agreement stating that Postdoctoral Training Fellows can only be employed for up  to 7 years as PDTF at the ICR, providing total postdoctoral experience (including previous employment at this level elsewhere) does not exceed 10 years

Lab Information:

Dr Anguraj Sadanandam’s Systems and Precision Cancer Medicine Team is investigating methods to classify pancreatic-, colorectal-, breast- and multiple other cancer patients into clinically relevant subgroups. Our interdisciplinary lab focuses on personalized medicine and companion diagnostics using cancer subtypes and evolution by integrating multi-omics (molecular and metabolism) and phenomics (phenotypes) data. We perform this by integrating wet-lab science with computational biology skills by cross-comparing and integrating high-throughput data (including whole tumour and single cell omics data and cross-species analysis) between patients and in vivo and in vitro models. 

We encourage all applicants to access the job pack attached for more detailed information regarding this role. You may contact Anguraj Sadanandam for further information by emailing anguraj.sadanandam@icr.ac.uk

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