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Research Fellow in Synthesis and Application of Photocaged DNA and RNA Technologies

UCL - Department of Chemistry

Location: London
Salary: The salary range will be £36,770 - £44,388 per annum, inclusive of London Allowance.
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 5th May 2022
Closes: 25th May 2022
Job Ref: 1884247
 

Fixed Term: This post is available for 14 months initially, to start anytime from now to October 2022 at the latest.

Applications are invited for a Research Fellow to work in the group of Dr Michael Booth in the Department of Chemistry at University College London. This is an exciting opportunity to join our new research team. The project will involve the generation of long wavelength light-activated nucleic acids for applications in biology and medicine. Light is a desirable remote stimulus, which allows for precise, bioorthogonal, and spatiotemporal control. While longer wavelength activation (for instance near-IR) has distinct advantages for future application, including higher tissue penetration and lower cytotoxicity.

The post holder will carry out the synthesis of long wavelength photocages followed by their incorporation into a range of nucleic acid technologies. They will then test their activity in both cell-free and cellular systems. We are seeking candidates with a background in synthetic chemistry and some experience with photochemistry, nucleic acids, and/or biological assays. Candidates should be able to work independently and have excellent written and oral communication skills in English. They will be expected to work with other group members, including offering supervision and support to undergraduate and postgraduate students.

This post is available for 14 months initially, to start anytime from now to October 2022 at the latest.

The successful candidate will have a PhD degree (or be about to be awarded a PhD) in an area of Chemistry, Chemical Biology or a related discipline. Experience with synthetic chemistry, excellent technical skills and a desire to work with nucleic acids are required. They will be required to work in a multidisciplinary, collaborative team and have effective written and verbal communication skills in English.

Please note, appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Research Assistant Grade 6B (salary £32,217 to £33,958 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.

Applicants should apply online. To access further details about the position and how to apply please click on the ‘Apply’ button above.

Informal enquiries should be addressed to Dr Michael Booth (m.j.booth@ucl.ac.uk).

Any queries on the application process can be directed to Hayley Dansey – h.dansey@ucl.ac.uk.

Closing Date: 25/5/2022. Latest time for the submission of applications: 23:59.

Interview Date: TBC

We particularly welcome female applicants and those from an ethnic minority, as they are under-represented within UCL at this level.

Our department holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality.

To apply click here  https://atsv7.wcn.co.uk/saf/login.cgi?owner=5041178&ownertype=fair&jcode=1884247&external=265697

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